Skip Header

Contribute Send feedback
Read comments (?) or add your own

C0ZW87 (C0ZW87_RHOE4) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr HAMAP MF_01201 EMBL BAH32622.1
Ordered Locus Names:RER_19140
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site581Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2871Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue581N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
C0ZW87 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 562A09B49B014ADC

FASTA40042,576
        10         20         30         40         50         60 
MTLAQGRAPK EPAEGKASRL DDAVGPQTEA VVDLDAIAHN VRVLREFAGD AALMAVIKAD 

        70         80         90        100        110        120 
GYNHGAVAVA RTALSAGARE LGVTTIAEAL VLREAGITAP VLAWLHGLDA DFSSAIRSDV 

       130        140        150        160        170        180 
EIGVSSPRHL AAVVDAARVL GQQATVTLKV DTGLNRNGVS RTEWPQMLDD LATARDEGTI 

       190        200        210        220        230        240 
RLRGVFSHLA HSDEPHHDVI DMQKQRLIEA VVDVRARGFE PEVVHLSNSA ATVTRPDLQF 

       250        260        270        280        290        300 
DMVRPGIAIY GLSPVPELGD FGLRPAMTLR AKVILVKKVA AGEGVSYGHQ WVAPHDTTLA 

       310        320        330        340        350        360 
LLPVGYADGL TRSLSGKFEV QLGGKRRQAV GRICMDQVLV DLGPDGDGVR EGDTAIFFGN 

       370        380        390        400 
GDHGEPNAQA WADVLDTIHY EVVTGIRGRT VRTYIGGETS

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH32622.1.
RefSeqYP_002765361.1. NC_012490.1.

3D structure databases

ProteinModelPortalC0ZW87.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZW87.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7713973.
GenomeReviewsGene locus RER_19140 in contig AP008957_GR.
KEGGrer:RER_19140.
PATRIC23190222. VBIRhoEry66701_2408.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEGTPVWV.
ProtClustDBPRK00053.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC0ZW87_RHOE4
AccessionPrimary (citable) accession number: C0ZW87
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info