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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:RER_17330
OrganismiRhodococcus erythropolis (strain PR4 / NBRC 100887)
Taxonomic identifieri234621 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
Proteomesi
  • UP000002204 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002144851 – 1168DNA-directed RNA polymerase subunit betaAdd BLAST1168

Proteomic databases

PRIDEiC0ZVQ6.

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi234621.RER_17330.

Structurei

3D structure databases

SMRiC0ZVQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiFMTWEGY.
OrthoDBiPOG091H01MI.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.40.270.10. 2 hits.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiView protein in InterPro
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNAP_su2_dom.
IPR037033. DNA-dir_RNAP_su2_hyb_sf.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR037034. RNA_pol_Rpb2_2_sf.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiView protein in Pfam
PF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiView protein in PROSITE
PS01166. RNA_POL_BETA. 1 hit.

Sequencei

Sequence statusi: Complete.

C0ZVQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEGRILAVS SQTKAVSGIP GAPKRVSFAK VREPLEVPGL LDVQTDSFEW
60 70 80 90 100
LIGAQSWRER AAALGDNAVS GGLEDILAEL SPIEDFNGTM SLSFSDPRFD
110 120 130 140 150
EVKASTDECK DKDMTYAAPL FVTAEFINNN TGEIKSQTVF MGDFPMMTDK
160 170 180 190 200
GTFIINGTER VVVSQLVRSP GVYFDMSVDK STEKDLHSVK VIPGRGAWLE
210 220 230 240 250
FDVDKRDTVG VRIDRKRRQP VTVLLKALGW TTEQITERFG FSEILMATLE
260 270 280 290 300
KDNTAGTDEA LLDIYRKLRP GEPPTKESAQ TLLENLFFKD KRYDLARVGR
310 320 330 340 350
YKINKKLGLN AGQPIVASTL TEEDIVATVE YLVRLHAGDT SMTAPGGVEV
360 370 380 390 400
PVEVDDIDHF GNRRLRTVGE LIQNQIRVGL SRMERVVRER MTTQDVEAIT
410 420 430 440 450
PQTLINIRPV VAAIREFFGT SQLSQFMDQN NPLSGLTHKR RLSALGPGGL
460 470 480 490 500
SRERAGLEVR DVHPSHYGRM CPIETPEGPN IGLIGSLSVY ARVNPFGFIE
510 520 530 540 550
TPYRRVVDGQ VTDEVDYLTA DEEDRHVVAQ ANSAIDREGR FTDSKILVRR
560 570 580 590 600
KGGEVEFVAS SDIDYMDVSP RQMVSVATAM IPFLEHDDAN RALMGANMQR
610 620 630 640 650
QAVPLVRSEA PLVGTGMELR AAVDAGDVII TEKTGVVEEI SADYVTVMAD
660 670 680 690 700
DGSRKTYRMR KFARSNQGTC ANQRPIVDEG QRVEAGQVLA DGPCTENGEM
710 720 730 740 750
ALGKNLLVAI MPWEGHNYED AIILSQRLVE EDVLTSIHIE EHEIDARDTK
760 770 780 790 800
LGAEEITRDI PNVSDEVLAD LDERGIIRIG AEVRDGDVLV GKVTPKGETE
810 820 830 840 850
LTPEERLLRA IFGEKAREVR DTSLKVPHGE TGKVIGIRVF SRDEDDDLPP
860 870 880 890 900
GVNELVRVYV AQKRKIQDGD KLAGRHGNKG VIGKILPQED MPFLSDGTPV
910 920 930 940 950
DIILNTHGVP RRMNIGQVLE THLGWIGKTG WNIQIASDGT RPDWAATLPE
960 970 980 990 1000
EMLSAPADSN IATPVFDGAK EDELTGLLGA TLPNRDGEQM VGPDGKATLF
1010 1020 1030 1040 1050
DGRSGEPFPY PVSVGYMYII KLHHLVDDKI HARSTGPYSM ITQQPLGGKA
1060 1070 1080 1090 1100
QFGGQRFGEM ECWAMQAYGA AYTLQELLTI KSDDVVGRVK VYEAIVKGEN
1110 1120 1130 1140 1150
IPEPGIPESF KVLLKELQSL CLNVEVLSSD GAAITMADGD DEDLERAAAN
1160
LGINLSRNEA ATVDDLAN
Length:1,168
Mass (Da):128,340
Last modified:May 26, 2009 - v1
Checksum:i11B2A4838DBFC92E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH32441.1.
RefSeqiWP_019744305.1. NC_012490.1.

Genome annotation databases

EnsemblBacteriaiBAH32441; BAH32441; RER_17330.
GeneIDi31541503.
KEGGirer:RER_17330.

Similar proteinsi

Entry informationi

Entry nameiRPOB_RHOE4
AccessioniPrimary (citable) accession number: C0ZVQ6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: November 22, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families