C0ZUN9 (C0ZUN9_RHOE4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative cobalamin-independent methionine synthase EMBL BAH32284.1
EC=2.1.1.14 EMBL BAH32284.1

Gene names

Ordered Locus Names:

RER_15760 EMBL BAH32284.1

Organism

Rhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP] EMBL BAH32284.1

Taxonomic identifier

234621 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus › Rhodococcus erythropolis

Protein attributes

Sequence length	768 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation By similarity. SAAS SAAS013215
Catalytic activity	5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine. SAAS SAAS013215
Pathway	Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1. SAAS SAAS013215

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Methionine biosynthesis SAAS SAAS013215
Ligand	Metal-binding SAAS SAAS013215 Zinc SAAS SAAS013215
Molecular function	Methyltransferase SAAS SAAS013215 EMBL BAH32284.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	methionine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C0ZUN9 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: C532D284222D733B	FASTA	768	86,009
	10 20 30 40 50 60 MSSSTAAFGS SVLGYPRIGP RRELKRALES YWHGTSDKDA LLAVAKELQE STWSELAATG 70 80 90 100 110 120 LSQVPGNTFS FYDHVLDNAL LFGAVPERFK PLEGALDPLD FYFTMARGRP DFPPLELVRF 130 140 150 160 170 180 FGTNYYYRQP EIDANTVFSL NSEALLDEFE RAKARGIELR PVIMGPVSLL LLSKVGPATE 190 200 210 220 230 240 KSDPNFTPLD LLDALLPEYE KLFEQLAKAG ATCVQLDEPS VTEDRTPEEL AALGRAYEKL 250 260 270 280 290 300 STAPLRPRLL VTGPYGKFGE ALNILAPTKI EAFGLDLVHG KITAEELAAV PNIKRKRIYA 310 320 330 340 350 360 GVVDGRNVWR VDRFNTLTYL NELKDVVPDL VVSTSSSLLH VPYDVLSEYD IPGDVADRLA 370 380 390 400 410 420 FAKQKVGEVV SLAKALTEGP SDKWRKRPTK VHFKLKHAVR ARVNAIKPED RVRAPYEERR 430 440 450 460 470 480 KAQQERLNLP LVPAQTLGSF PQTDAIRQAR YELGQGRLEW DDYYKRIQEE IERTIRLQED 490 500 510 520 530 540 IGLDVFVHGE HERNDMVQYF AELLEGYAFT HNGWVQAYGS RCTRPPILYG DIARPKPMTV 550 560 570 580 590 600 EWIAYAQSLT DKPVKGMLTG PVTMIARSFV RQDQPLYETA EQLALVIRDE IADLEAAGIA 610 620 630 640 650 660 IIQVDEPAIR ELLPLREDGR EAYLEWAVDA FRLATGGAKP ETQIHTHLTY SARSSVVDAI 670 680 690 700 710 720 ERLDADVTAI VATRSITWVL EALKEGALTH GVGPGVYESR SARIPDIDEL DELLTEASES 730 740 750 760 ISLDRLWANP DGGLKTRHPW QLEPSLRNMV AAARRLRRRA EQAERDAG

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008957 Genomic DNA. Translation: BAH32284.1.
RefSeq	YP_002765023.1. NC_012490.1.
3D structure databases
ProteinModelPortal	C0ZUN9.
ModBase	Search...
Protein-protein interaction databases
STRING	234621.RER_15760.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAH32284; BAH32284; RER_15760.
GeneID	7713657.
KEGG	rer:RER_15760.
PATRIC	23189520. VBIRhoEry66701_2061.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0620.
HOGENOM	HOG000246221.
KO	K00549.
OMA	GEHERND.
ProtClustDB	PRK05222.
Enzyme and pathway databases
BioCyc	RERY234621:GHDE-1409-MONOMER.
UniPathway	UPA00051; UER00082.
Family and domain databases
InterPro	IPR013215. Cbl-indep_Met_Synth_N. IPR006276. Cobalamin-indep_Met_synthase. IPR002629. Methionine_synth. [Graphical view]
Pfam	PF08267. Meth_synt_1. 1 hit. PF01717. Meth_synt_2. 1 hit. [Graphical view]
PIRSF	PIRSF000382. MeTrfase_B12_ind. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C0ZUN9_RHOE4

Accession

Primary (citable) accession number: C0ZUN9

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)