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C0ZUN9

- C0ZUN9_RHOE4

UniProt

C0ZUN9 - C0ZUN9_RHOE4

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Protein

5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

Gene

RER_15760

Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.SAAS annotation

Catalytic activityi

5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine.SAAS annotation

Pathwayi

GO - Molecular functioni

  1. 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. methionine biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotationImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Methionine biosynthesisSAAS annotation

Keywords - Ligandi

Metal-bindingSAAS annotation, ZincSAAS annotation

Enzyme and pathway databases

BioCyciRERY234621:GHDE-1595-MONOMER.
UniPathwayiUPA00051; UER00082.

Names & Taxonomyi

Protein namesi
Recommended name:
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseSAAS annotation (EC:2.1.1.14SAAS annotation)
Gene namesi
Ordered Locus Names:RER_15760Imported
OrganismiRhodococcus erythropolis (strain PR4 / NBRC 100887)Imported
Taxonomic identifieri234621 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002204: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi234621.RER_15760.

Structurei

3D structure databases

ProteinModelPortaliC0ZUN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0620.
HOGENOMiHOG000246221.
KOiK00549.
OMAiVGPGVYE.
OrthoDBiEOG6FFS3G.

Family and domain databases

InterProiIPR013215. Cbl-indep_Met_Synth_N.
IPR006276. Cobalamin-indep_Met_synthase.
IPR002629. Met_Synth_C/arc.
[Graphical view]
PfamiPF08267. Meth_synt_1. 1 hit.
PF01717. Meth_synt_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000382. MeTrfase_B12_ind. 1 hit.

Sequencei

Sequence statusi: Complete.

C0ZUN9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSSTAAFGS SVLGYPRIGP RRELKRALES YWHGTSDKDA LLAVAKELQE
60 70 80 90 100
STWSELAATG LSQVPGNTFS FYDHVLDNAL LFGAVPERFK PLEGALDPLD
110 120 130 140 150
FYFTMARGRP DFPPLELVRF FGTNYYYRQP EIDANTVFSL NSEALLDEFE
160 170 180 190 200
RAKARGIELR PVIMGPVSLL LLSKVGPATE KSDPNFTPLD LLDALLPEYE
210 220 230 240 250
KLFEQLAKAG ATCVQLDEPS VTEDRTPEEL AALGRAYEKL STAPLRPRLL
260 270 280 290 300
VTGPYGKFGE ALNILAPTKI EAFGLDLVHG KITAEELAAV PNIKRKRIYA
310 320 330 340 350
GVVDGRNVWR VDRFNTLTYL NELKDVVPDL VVSTSSSLLH VPYDVLSEYD
360 370 380 390 400
IPGDVADRLA FAKQKVGEVV SLAKALTEGP SDKWRKRPTK VHFKLKHAVR
410 420 430 440 450
ARVNAIKPED RVRAPYEERR KAQQERLNLP LVPAQTLGSF PQTDAIRQAR
460 470 480 490 500
YELGQGRLEW DDYYKRIQEE IERTIRLQED IGLDVFVHGE HERNDMVQYF
510 520 530 540 550
AELLEGYAFT HNGWVQAYGS RCTRPPILYG DIARPKPMTV EWIAYAQSLT
560 570 580 590 600
DKPVKGMLTG PVTMIARSFV RQDQPLYETA EQLALVIRDE IADLEAAGIA
610 620 630 640 650
IIQVDEPAIR ELLPLREDGR EAYLEWAVDA FRLATGGAKP ETQIHTHLTY
660 670 680 690 700
SARSSVVDAI ERLDADVTAI VATRSITWVL EALKEGALTH GVGPGVYESR
710 720 730 740 750
SARIPDIDEL DELLTEASES ISLDRLWANP DGGLKTRHPW QLEPSLRNMV
760
AAARRLRRRA EQAERDAG
Length:768
Mass (Da):86,009
Last modified:May 26, 2009 - v1
Checksum:iC532D284222D733B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH32284.1.
RefSeqiYP_002765023.1. NC_012490.1.

Genome annotation databases

EnsemblBacteriaiBAH32284; BAH32284; RER_15760.
GeneIDi7713657.
KEGGirer:RER_15760.
PATRICi23189520. VBIRhoEry66701_2061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH32284.1 .
RefSeqi YP_002765023.1. NC_012490.1.

3D structure databases

ProteinModelPortali C0ZUN9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 234621.RER_15760.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAH32284 ; BAH32284 ; RER_15760 .
GeneIDi 7713657.
KEGGi rer:RER_15760.
PATRICi 23189520. VBIRhoEry66701_2061.

Phylogenomic databases

eggNOGi COG0620.
HOGENOMi HOG000246221.
KOi K00549.
OMAi VGPGVYE.
OrthoDBi EOG6FFS3G.

Enzyme and pathway databases

UniPathwayi UPA00051 ; UER00082 .
BioCyci RERY234621:GHDE-1595-MONOMER.

Family and domain databases

InterProi IPR013215. Cbl-indep_Met_Synth_N.
IPR006276. Cobalamin-indep_Met_synthase.
IPR002629. Met_Synth_C/arc.
[Graphical view ]
Pfami PF08267. Meth_synt_1. 1 hit.
PF01717. Meth_synt_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000382. MeTrfase_B12_ind. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.
  2. "Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4."
    Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N., Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K., Ito M., Narita H., Tago S., Fujita N., Harayama S.
    Environ. Microbiol. 8:334-346(2006)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.

Entry informationi

Entry nameiC0ZUN9_RHOE4
AccessioniPrimary (citable) accession number: C0ZUN9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: November 26, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3