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C0ZUN9

- C0ZUN9_RHOE4

UniProt

C0ZUN9 - C0ZUN9_RHOE4

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Protein
Submitted name:

Putative cobalamin-independent methionine synthase

Gene
RER_15760
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation By similarity.SAAS annotations

Catalytic activityi

5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. methionine biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotationsImported, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Methionine biosynthesisSAAS annotations

Keywords - Ligandi

Metal-bindingSAAS annotations, ZincSAAS annotations

Enzyme and pathway databases

BioCyciRERY234621:GHDE-1595-MONOMER.
UniPathwayiUPA00051; UER00082.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative cobalamin-independent methionine synthaseImported (EC:2.1.1.14Imported)
Gene namesi
Ordered Locus Names:RER_15760Imported
OrganismiRhodococcus erythropolis (strain PR4 / NBRC 100887)Imported
Taxonomic identifieri234621 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002204: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi234621.RER_15760.

Structurei

3D structure databases

ProteinModelPortaliC0ZUN9.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0620.
HOGENOMiHOG000246221.
KOiK00549.
OMAiVGPGVYE.
OrthoDBiEOG6FFS3G.

Family and domain databases

InterProiIPR013215. Cbl-indep_Met_Synth_N.
IPR006276. Cobalamin-indep_Met_synthase.
IPR002629. Met_Synth_C/arc.
[Graphical view]
PfamiPF08267. Meth_synt_1. 1 hit.
PF01717. Meth_synt_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000382. MeTrfase_B12_ind. 1 hit.

Sequencei

Sequence statusi: Complete.

C0ZUN9-1 [UniParc]FASTAAdd to Basket

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MSSSTAAFGS SVLGYPRIGP RRELKRALES YWHGTSDKDA LLAVAKELQE    50
STWSELAATG LSQVPGNTFS FYDHVLDNAL LFGAVPERFK PLEGALDPLD 100
FYFTMARGRP DFPPLELVRF FGTNYYYRQP EIDANTVFSL NSEALLDEFE 150
RAKARGIELR PVIMGPVSLL LLSKVGPATE KSDPNFTPLD LLDALLPEYE 200
KLFEQLAKAG ATCVQLDEPS VTEDRTPEEL AALGRAYEKL STAPLRPRLL 250
VTGPYGKFGE ALNILAPTKI EAFGLDLVHG KITAEELAAV PNIKRKRIYA 300
GVVDGRNVWR VDRFNTLTYL NELKDVVPDL VVSTSSSLLH VPYDVLSEYD 350
IPGDVADRLA FAKQKVGEVV SLAKALTEGP SDKWRKRPTK VHFKLKHAVR 400
ARVNAIKPED RVRAPYEERR KAQQERLNLP LVPAQTLGSF PQTDAIRQAR 450
YELGQGRLEW DDYYKRIQEE IERTIRLQED IGLDVFVHGE HERNDMVQYF 500
AELLEGYAFT HNGWVQAYGS RCTRPPILYG DIARPKPMTV EWIAYAQSLT 550
DKPVKGMLTG PVTMIARSFV RQDQPLYETA EQLALVIRDE IADLEAAGIA 600
IIQVDEPAIR ELLPLREDGR EAYLEWAVDA FRLATGGAKP ETQIHTHLTY 650
SARSSVVDAI ERLDADVTAI VATRSITWVL EALKEGALTH GVGPGVYESR 700
SARIPDIDEL DELLTEASES ISLDRLWANP DGGLKTRHPW QLEPSLRNMV 750
AAARRLRRRA EQAERDAG 768
Length:768
Mass (Da):86,009
Last modified:May 26, 2009 - v1
Checksum:iC532D284222D733B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008957 Genomic DNA. Translation: BAH32284.1.
RefSeqiYP_002765023.1. NC_012490.1.

Genome annotation databases

EnsemblBacteriaiBAH32284; BAH32284; RER_15760.
GeneIDi7713657.
KEGGirer:RER_15760.
PATRICi23189520. VBIRhoEry66701_2061.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008957 Genomic DNA. Translation: BAH32284.1 .
RefSeqi YP_002765023.1. NC_012490.1.

3D structure databases

ProteinModelPortali C0ZUN9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 234621.RER_15760.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAH32284 ; BAH32284 ; RER_15760 .
GeneIDi 7713657.
KEGGi rer:RER_15760.
PATRICi 23189520. VBIRhoEry66701_2061.

Phylogenomic databases

eggNOGi COG0620.
HOGENOMi HOG000246221.
KOi K00549.
OMAi VGPGVYE.
OrthoDBi EOG6FFS3G.

Enzyme and pathway databases

UniPathwayi UPA00051 ; UER00082 .
BioCyci RERY234621:GHDE-1595-MONOMER.

Family and domain databases

InterProi IPR013215. Cbl-indep_Met_Synth_N.
IPR006276. Cobalamin-indep_Met_synthase.
IPR002629. Met_Synth_C/arc.
[Graphical view ]
Pfami PF08267. Meth_synt_1. 1 hit.
PF01717. Meth_synt_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000382. MeTrfase_B12_ind. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887.

Entry informationi

Entry nameiC0ZUN9_RHOE4
AccessioniPrimary (citable) accession number: C0ZUN9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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