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Protein

Methionyl-tRNA formyltransferase

Gene

RER_09720

Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity).SAAS annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseSAAS annotationImported

Keywords - Biological processi

Protein biosynthesisSAAS annotation

Enzyme and pathway databases

BioCyciRERY234621:GHDE-989-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseSAAS annotation (EC:2.1.2.9SAAS annotation)
Gene namesi
Ordered Locus Names:RER_09720Imported
OrganismiRhodococcus erythropolis (strain PR4 / NBRC 100887)Imported
Taxonomic identifieri234621 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
ProteomesiUP000002204 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi234621.RER_09720.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0223.
HOGENOMiHOG000261177.
KOiK00604.
OMAiFIIANYQ.
OrthoDBiEOG6B09WV.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
InterProiIPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERiPTHR11138. PTHR11138. 1 hit.
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.

Sequencei

Sequence statusi: Complete.

C0ZRD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVATLGYQT WGHRTLQALI DSDHEVVLAI THPKSEHVYE QMWADSVADL
60 70 80 90 100
AAENGVPVHV ANKPDDAFKA ALAEAAPDII VANNWRTWLP AEVFDAPKYG
110 120 130 140 150
TLNIHDSLLP KYTGFSPLIW ALINGEEEVG LTAHLMDEEL DAGDIVLQRS
160 170 180 190 200
TTVGPTDTVT DLFHRTIDMI GPITLDALDL IASGRTDWTP QDRSQATFFH
210 220 230 240 250
KRAPQDSHVD WSWPAEVIER FVRAQSDPYP NAFAEFKGRR IRILKASVSR
260 270 280 290 300
GHYGGTPGRV FIQEDDGMVI VAGPDAWSGK NKGLRIERVR LDDGSEYTAA
310
EFFPHGGGYL T
Length:311
Mass (Da):34,484
Last modified:May 26, 2009 - v1
Checksum:iAAFB5A9CFDB95DB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH31680.1.
RefSeqiWP_020906323.1. NC_012490.1.

Genome annotation databases

EnsemblBacteriaiBAH31680; BAH31680; RER_09720.
GeneIDi7712883.
KEGGirer:RER_09720.
PATRICi23188250. VBIRhoEry66701_1428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH31680.1.
RefSeqiWP_020906323.1. NC_012490.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi234621.RER_09720.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH31680; BAH31680; RER_09720.
GeneIDi7712883.
KEGGirer:RER_09720.
PATRICi23188250. VBIRhoEry66701_1428.

Phylogenomic databases

eggNOGiCOG0223.
HOGENOMiHOG000261177.
KOiK00604.
OMAiFIIANYQ.
OrthoDBiEOG6B09WV.

Enzyme and pathway databases

BioCyciRERY234621:GHDE-989-MONOMER.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
InterProiIPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERiPTHR11138. PTHR11138. 1 hit.
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.
  2. "Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4."
    Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N., Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K., Ito M., Narita H., Tago S., Fujita N., Harayama S.
    Environ. Microbiol. 8:334-346(2006)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.

Entry informationi

Entry nameiC0ZRD0_RHOE4
AccessioniPrimary (citable) accession number: C0ZRD0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: July 22, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.