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C0ZJI8 (C0ZJI8_BREBN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818

EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818 EMBL BAH45563.1
Ordered Locus Names:BBR47_45860
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesPaenibacillaceaeBrevibacillus

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818 SAAS SAAS016856

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818 SAAS SAAS016856

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818 SAAS SAAS016856

Subcellular location

Cytoplasm By similarity HAMAP MF_00818 SAAS SAAS016856.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
C0ZJI8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 508BDACC9A6EE81C

FASTA16519,341
        10         20         30         40         50         60 
MAHQQERDLS SLTLLGNQGT TYNYSYDPSV LESFDNKHPY RDYFVKFNCP EFTSLCPITG 

        70         80         90        100        110        120 
QPDFATIYIS YIPDIKMVES KSLKLYLFSF RNHGDFHEDC VNVIMNDLIK LMDPRYIEVW 

       130        140        150        160 
GKFTPRGGIS IDPYCNYGKP GTKYEEMASH RMMNHDMYPE KVDNR 

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008955 Genomic DNA. Translation: BAH45563.1.
RefSeqYP_002774067.1. NC_012491.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZJI8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7718709.
GenomeReviewsGene locus BBR47_45860 in contig AP008955_GR.
KEGGbbe:BBR47_45860.
PATRIC21239518. VBIBreBre96763_4545.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACINTILL.
ProtClustDBCLSK2547406.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC0ZJI8_BREBN
AccessionPrimary (citable) accession number: C0ZJI8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)