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Protein

Signal peptidase I

Gene

BBR47_36110

Organism
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseUniRule annotation

Enzyme and pathway databases

BioCyciBBRE358681:GHYS-3742-MONOMER.

Protein family/group databases

MEROPSiS26.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Signal peptidase IUniRule annotation (EC:3.4.21.89UniRule annotation)
Gene namesi
Ordered Locus Names:BBR47_36110Imported
OrganismiBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)Imported
Taxonomic identifieri358681 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus
ProteomesiUP000001877 Componenti: Chromosome

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type II membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei21 – 4222HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi358681.BBR47_36110.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S26 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiGKPYEEP.
OrthoDBiEOG622PW8.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0ZFM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEITSSHK KKNELWEWIK ALGIALILAF FIRTFLFAPF IVEGESMEST
60 70 80 90 100
LHNSEKLVVN KAIYFLQDPT PGEIIVFHAE KERDYIKRVI AVEGDTVEVK
110 120 130 140 150
NDQLLVNGKV VEEPYLAQSK EQAKQQGEPF FTHDFPPVQI PADHIFVMGD
160 170 180
NRLNSHDSRA IGPVAVSTVV GRAEFTFWPV AGIRLTR
Length:187
Mass (Da):21,194
Last modified:May 26, 2009 - v1
Checksum:i166692CEAD8BD508
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA. Translation: BAH44588.1.
RefSeqiWP_015891885.1. NC_012491.1.

Genome annotation databases

EnsemblBacteriaiBAH44588; BAH44588; BBR47_36110.
KEGGibbe:BBR47_36110.
PATRICi21237520. VBIBreBre96763_3577.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA. Translation: BAH44588.1.
RefSeqiWP_015891885.1. NC_012491.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi358681.BBR47_36110.

Protein family/group databases

MEROPSiS26.003.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH44588; BAH44588; BBR47_36110.
KEGGibbe:BBR47_36110.
PATRICi21237520. VBIBreBre96763_3577.

Phylogenomic databases

eggNOGiCOG0681.
HOGENOMiHOG000003673.
KOiK03100.
OMAiGKPYEEP.
OrthoDBiEOG622PW8.

Enzyme and pathway databases

BioCyciBBRE358681:GHYS-3742-MONOMER.

Family and domain databases

Gene3Di2.10.109.10. 2 hits.
InterProiIPR000223. Pept_S26A_signal_pept_1.
IPR019758. Pept_S26A_signal_pept_1_CS.
IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
IPR028360. Peptidase_S24/S26_b-rbn.
IPR019759. Peptidase_S24_S26.
IPR015927. Peptidase_S24_S26A/B/C.
[Graphical view]
PANTHERiPTHR12383. PTHR12383. 1 hit.
PfamiPF00717. Peptidase_S24. 1 hit.
[Graphical view]
PRINTSiPR00727. LEADERPTASE.
SUPFAMiSSF51306. SSF51306. 1 hit.
TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
PROSITEiPS00501. SPASE_I_1. 1 hit.
PS00761. SPASE_I_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Brevibacillus brevis strain 47, complete genome."
    Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H.
    , Udaka S., Tanikawa S., Fujita N.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 47 / JCM 6285 / NBRC 100599Imported.

Entry informationi

Entry nameiC0ZFM9_BREBN
AccessioniPrimary (citable) accession number: C0ZFM9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: July 22, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.