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C0ZDJ1 (C0ZDJ1_BREBN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Catalase-peroxidase HAMAP MF_01961
Short name=CP HAMAP MF_01961
EC=1.11.1.21 HAMAP MF_01961
Alternative name(s):
Peroxidase/catalase HAMAP MF_01961
Gene names
Name:katG HAMAP MF_01961
Ordered Locus Names:BBR47_28730
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length727 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity By similarity. HAMAP MF_01961

Catalytic activity

2 H2O2 = O2 + 2 H2O. HAMAP MF_01961 RuleBase RU003451 SAAS SAAS019794

Donor + H2O2 = oxidized donor + 2 H2O. HAMAP MF_01961 SAAS SAAS019794

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per dimer By similarity. HAMAP MF_01961 SAAS SAAS019794

Subunit structure

Homodimer or homotetramer By similarity. HAMAP MF_01961

Post-translational modification

The covalent Trp-Tyr-Met adduct is important for the catalase, but not the peroxidase activity of the enzyme By similarity. HAMAP MF_01961

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily. HAMAP MF_01961 RuleBase RU003451

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1021Proton acceptor By similarity HAMAP MF_01961
Metal binding2651Iron (heme axial ligand) By similarity HAMAP MF_01961
Site981Transition state stabilizer By similarity HAMAP MF_01961

Amino acid modifications

Cross-link101 ↔ 224Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-250) By similarity HAMAP MF_01961
Cross-link224 ↔ 250Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-101) By similarity HAMAP MF_01961

Sequences

Sequence LengthMass (Da)Tools
C0ZDJ1 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 41AB15A04A9BEDD4

FASTA72780,061
        10         20         30         40         50         60 
MDSMATANTG KCPFSHGSTT NHNPSATSNK HWWPNQLNLN ILHQHDRKSN PMGEEFDYAE 

        70         80         90        100        110        120 
EFEKLDYQAL KQDLYDLMTN SQDWWPADYG HYGPLFIRMA WHSAGTYRTG DGRGGAGTGT 

       130        140        150        160        170        180 
QRFAPLNSWP DNANLDKARR LLWPIKQKYG NKISWADLYI LAGNAAIESM GGKTIGFGGG 

       190        200        210        220        230        240 
RADVWHPEED IYWGAEKEWL GDNRYTGDRD LENPLAAVQM GLIYVNPEGP NGNPDPLASA 

       250        260        270        280        290        300 
RDIRETFKRM GMNDEETVAL VAGGHTFGKA HGAGDAALVG PEPEAAPLEA MGLGWQSTHG 

       310        320        330        340        350        360 
SGKGRDAITS GIEGAWTANP TQWDNGFFEL LFGYEWELTK SPAGAHQWVA VNPADEHLAP 

       370        380        390        400        410        420 
DAEDASVRVP TMMTTADMAL RMDPAYEKIS RRYYENPEEF ADAFATAWFK LTHRDMGPRS 

       430        440        450        460        470        480 
RYLGPEVPEE DFIWQDPVPA AEYELTDADV AELKTRILDS GLTVSELVTT SWASASTFRG 

       490        500        510        520        530        540 
SDMRGGSNGA RIRLAPQKEW EVNEPKKLEK VLTILGVIQE DFGKKVSMAD LIVLGGSAAV 

       550        560        570        580        590        600 
EKAAQDAGFD VTVPFAPGRG DATQEQTDAE SFAVLEPIAD GFRNYQKKQY RVSPADLLID 

       610        620        630        640        650        660 
KAQLLNLTAP EMTALVGGMR VIGTNHGGTQ HGVFTDRVGT LTNDFFVNLL DMGIQWKPVD 

       670        680        690        700        710        720 
GGVFEGRDSK TGEVVRTATA VDLVFGSNSV LRAIAEVYAQ DDNKEKFVRD FIAAWVKVMN 


ADRFDLK

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References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008955 Genomic DNA. Translation: BAH43850.1.
RefSeqYP_002772354.1. NC_012491.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZDJ1.

Protein family/group databases

PeroxiBase7326. BbrCP01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7715531.
GenomeReviewsGene locus BBR47_28730 in contig AP008955_GR.
KEGGbbe:BBR47_28730.
PATRIC21236086. VBIBreBre96763_2863.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAWPNALNL.
ProtClustDBPRK15061.

Family and domain databases

HAMAPMF_01961. Catal_peroxid.
[Tree]
InterProIPR000763. Catalase_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
KOK03782.
PfamPF00141. peroxidase. 2 hits.
[Graphical view]
PRINTSPR00460. BPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMSSF48113. Peroxidase_super. 2 hits.
TIGRFAMsTIGR00198. Cat_per_HPI. 1 hit.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0ZDJ1_BREBN
AccessionPrimary (citable) accession number: C0ZDJ1
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info