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C0ZDG3 (C0ZDG3_BREBN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL BAH43822.1
Ordered Locus Names:BBR47_28450 EMBL BAH43822.1
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain101 – 300200ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding127 – 18155ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2491Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2671Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2671Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2691Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C0ZDG3 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 8A9C87122C56D67C

FASTA31634,521
        10         20         30         40         50         60 
MKIGVIMGGI SSEREVSLKT GQEMINHLDR SRYEAVPIVI TQRADLITQV QQAGIDFALL 

        70         80         90        100        110        120 
ALHGQYGEDG TVQGALETLG IPYTGSGVLA SSLCMNKQLS KMLLKTAGIQ TPAGLYWKDV 

       130        140        150        160        170        180 
YDPQAVEQLG YPVIVKPNLG GSSIGVQLVQ NEKELLSAVQ EASYLDQGIL IEPYLKGTEL 

       190        200        210        220        230        240 
TCAILDGEVL PIIGIRSAHS EWFDYRAKYE DGGAEEKVIE LPPDIQQRVR EAALASYQLL 

       250        260        270        280        290        300 
QCKVYARVDM ILCQDMPLCQ DMPYVLEVNT LPGMTANSLF PKSAAAAGMT FTQVLDRIIA 

       310 
SSLHERKREW GNSANG 

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 47 / JCM 6285 / NBRC 100599.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008955 Genomic DNA. Translation: BAH43822.1.
RefSeqYP_002772326.1. NC_012491.1.

3D structure databases

ProteinModelPortalC0ZDG3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING358681.BBR47_28450.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAH43822; BAH43822; BBR47_28450.
GeneID7715508.
KEGGbbe:BBR47_28450.
PATRIC21236032. VBIBreBre96763_2836.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMADRIQAND.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycBBRE358681:GHYS-2973-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0ZDG3_BREBN
AccessionPrimary (citable) accession number: C0ZDG3
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)