C0ZCE3 (C0ZCE3_BREBN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134 EMBL BAH43452.1
Ordered Locus Names:	BBR47_24750

Organism

Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]

Taxonomic identifier

358681 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 SAAS SAAS013798 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C0ZCE3 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 7632711387BA57AC	FASTA	266	29,387
	10 20 30 40 50 60 MLRKIVEKKR EEIARLYTDT TVSALLYATK EVQRPRGFRQ ALETSVRPVS VIAEVKKASP 70 80 90 100 110 120 SKGLIRPDFQ AVTIAKAYQA AQAECLSVLT DESFFQGSLS YLRQIHEVVD RPLLRKDFLL 130 140 150 160 170 180 DEIQVVEARA AGADCVLLIA AILDRETLRH LNQTAEELGM DVLIEVHDKR ECELVFQAME 190 200 210 220 230 240 PKLLGINNRN LNTFQTDLAV THELIAELPA SLTIVSESGI STPADIENVQ SAGARAVLVG 250 260 EHFMRQTDVE RAVIDLVGEA APGVSV

References

[1]

"Brevibacillus brevis strain 47, complete genome." Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. , Udaka S., Tanikawa S., Fujita N. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008955 Genomic DNA. Translation: BAH43452.1.
RefSeq	YP_002771956.1. NC_012491.1.
3D structure databases
ProteinModelPortal	C0ZCE3.
ModBase	Search...
Protein-protein interaction databases
STRING	C0ZCE3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7720761.
GenomeReviews	Gene locus BBR47_24750 in contig AP008955_GR.
KEGG	bbe:BBR47_24750.
PATRIC	21235272. VBIBreBre96763_2459.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MRKDDVT.
ProtClustDB	CLSK2547241.
Family and domain databases
HAMAP	MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C0ZCE3_BREBN

Accession

Primary (citable) accession number: C0ZCE3

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)