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C0ZCD8 (AROC_BREBN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:BBR47_24700
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 387387Chorismate synthase HAMAP MF_00300
PRO_1000132756

Sequences

Sequence LengthMass (Da)Tools
C0ZCD8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 47D6AD907C2FC9FF

FASTA38742,547
        10         20         30         40         50         60 
MRYLTAGESH GPQLTAIIEG VPSNLPISIE EINEQLARRQ KGHGRGRRMQ IEKDQVKILS 

        70         80         90        100        110        120 
GVRHGYTTGA PITLVVENKD WTHWQGIMSA EPVEEGSEEK RRVSRPRPGH ADLNGAIKYH 

       130        140        150        160        170        180 
QRDMRNILER SSARETTVRV AVGAVARQLL AQFGIRIGGQ VLQINEIVAK RQEVSLDELI 

       190        200        210        220        230        240 
ARTEESPVRC LDKEAEPLMM AAIDKAKEDG DSLGGTVEVI VEGVPIGLGS HVQWDRKLDG 

       250        260        270        280        290        300 
RLAQAIMSIQ AFKGVEIGIG FEAAGLKGSQ VHDEIVWNEE TGYSRKTNRA GGLEGGMTTG 

       310        320        330        340        350        360 
MPVVVRGVMK PIPTLYKPLM SVDIDSREPF SASIERSDSC AVPAASVVAE AVVAWEIANA 

       370        380 
MCEKFPSDSL DDMEENVRQY RAYTEKF

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 47 / JCM 6285 / NBRC 100599.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008955 Genomic DNA. Translation: BAH43447.1.
RefSeqYP_002771951.1. NC_012491.1.

3D structure databases

ProteinModelPortalC0ZCD8.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZCD8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7716984.
GenomeReviewsGene locus BBR47_24700 in contig AP008955_GR.
KEGGbbe:BBR47_24700.
PATRIC21235262. VBIBreBre96763_2454.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAMLRWLTA.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_BREBN
AccessionPrimary (citable) accession number: C0ZCD8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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