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C0Z8I6 (MTLD_BREBN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:BBR47_56360
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length386 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 386386Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000124384

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
C0Z8I6 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 272CCF9C59A3EC1F

FASTA38642,019
        10         20         30         40         50         60 
MLAVHFGAGN IGRGFIGQLL QKAGYEIAFV DVNAALVDEL NERKMYRVQL ATTGKPESVV 

        70         80         90        100        110        120 
EGVRAINGQD VAAVAEAIAT ADLVTTAVGP NILPHIAGAI AAGITQRLTV HARPLNVIAC 

       130        140        150        160        170        180 
ENMIGGSEKL KEHVYEHLTE SVQAQAAQWI GFPNAAVDRI VPLQQHADKL LVMVEPFFEW 

       190        200        210        220        230        240 
VVDSSQIVGE VPAIEGVTYV EDLAPYIERK LFTVNTGHAV IAYLGYQLGM KTIDEAMRDD 

       250        260        270        280        290        300 
RIVQATRGAL QETGALLAAK YGFDPQVHGQ YVEKILGRYT NPLLSDDIVR VARSPIRKLS 

       310        320        330        340        350        360 
QHDRLVGPAL QCMEKGMNAS YLGLAIAAAL AFDYPEDAES ARIQASLKEF GWENTLHNCT 

       370        380 
GIPAGHPLEE IVREQARRLK EWSGSH

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 47 / JCM 6285 / NBRC 100599.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008955 Genomic DNA. Translation: BAH46613.1.
RefSeqYP_002775117.1. NC_012491.1.

3D structure databases

ProteinModelPortalC0Z8I6.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0Z8I6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7716324.
GenomeReviewsGene locus BBR47_56360 in contig AP008955_GR.
KEGGbbe:BBR47_56360.
PATRIC21241590. VBIBreBre96763_5570.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFANTAVD.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_BREBN
AccessionPrimary (citable) accession number: C0Z8I6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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