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Protein

Probable transaldolase

Gene

tal

Organism
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:BBR47_54880
OrganismiBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Taxonomic identifieri358681 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus
Proteomesi
  • UP000001877 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001984671 – 214Probable transaldolaseAdd BLAST214

Interactioni

Protein-protein interaction databases

STRINGi358681.BBR47_54880.

Structurei

3D structure databases

SMRiC0Z838.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3. Bacteria.
COG0176. LUCA.
HOGENOMiHOG000226073.
KOiK00616.
OMAiVRHPMHV.
OrthoDBiPOG091H04ZO.

Family and domain databases

CDDicd00956. Transaldolase_FSA. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00494. Transaldolase_3b. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR022999. Transaldolase_3B.
IPR004731. Transaldolase_3B/F6P_aldolase.
IPR018225. Transaldolase_AS.
IPR033919. TSA/FSA_arc/bac.
PANTHERiPTHR10683. PTHR10683. 2 hits.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
TIGRFAMsiTIGR00875. fsa_talC_mipB. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C0Z838-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFLIDTANV EEIREIHEWG VLAGVTTNPS LVAKEGRDFV ETLKEILDIV
60 70 80 90 100
DGPISAEVIS TDAKGMIEEG EKLAALSKNI VIKLPMTAEG LKATKYFAKR
110 120 130 140 150
KIRTNVTLVF SANQALLAAR AGASFVSPFL GRLDDIGQDG MQLIEDIAEI
160 170 180 190 200
FSVHGIDTEI IAASVRHPVH VTEAARRGSH FATIPAKVFK QLIAHPLTDS
210
GLEKFLADWA SMQK
Length:214
Mass (Da):23,333
Last modified:May 26, 2009 - v1
Checksum:i34864D0BA0A2EC9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA. Translation: BAH46465.1.
RefSeqiWP_015893657.1. NC_012491.1.

Genome annotation databases

EnsemblBacteriaiBAH46465; BAH46465; BBR47_54880.
GeneIDi29262708.
KEGGibbe:BBR47_54880.

Similar proteinsi

Entry informationi

Entry nameiTAL_BREBN
AccessioniPrimary (citable) accession number: C0Z838
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: October 25, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome