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C0Z819 (C0Z819_BREBN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase HAMAP MF_00051
Short name=SHMT HAMAP MF_00051
Short name=Serine methylase HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA HAMAP MF_00051 EMBL BAH46446.1
Ordered Locus Names:BBR47_54690
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2271N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
C0Z819 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 4274C69A8A5FD1C4

FASTA41645,382
        10         20         30         40         50         60 
MLDFLRKQDP QVMEAVQLEL GRQRDKIELI ASENFVSRAV MEAMGTVLTN KYAEGYPGRR 

        70         80         90        100        110        120 
YYGGCEYVDI VENIARDRVK EIFGAEHANV QPHSGAQANM AVYFTILQPG DTVLGMNLSH 

       130        140        150        160        170        180 
GGHLTHGSAV NFSGTLYNFV DYGVDEDTHL INYEDVRAKA LEHKPKLIVA GASAYPRTID 

       190        200        210        220        230        240 
FAKFREIADE VGAYFMVDMA HIAGLVAAGL HPNPVPHAHF VTSTTHKTLR GPRGGLILCK 

       250        260        270        280        290        300 
EEFAKGIDKS VFPGVQGGPL MHVIAAKAVA FGENLQPEFK DYAARIIKNA RAFAESLTAE 

       310        320        330        340        350        360 
GLTLVSGGTD NHLVLIDVSK IGLTGKVAEH LLDEVSITTN KNTIPYDTQS PFVTSGVRMG 

       370        380        390        400        410 
TPAVTSRGFD EEAMKEVAAI IALTLKNPED AAKHEEARQR VAALCQRFPM YEGLNI

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008955 Genomic DNA. Translation: BAH46446.1.
RefSeqYP_002774950.1. NC_012491.1.

3D structure databases

ProteinModelPortalC0Z819.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0Z819.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7720789.
GenomeReviewsGene locus BBR47_54690 in contig AP008955_GR.
KEGGbbe:BBR47_54690.
PATRIC21241258. VBIBreBre96763_5404.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAIFNAGYA.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0Z819_BREBN
AccessionPrimary (citable) accession number: C0Z819
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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