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Protein
Submitted name:

Precorrin-2 dehydrogenase/ferrochelatase

Gene

BBR47_12580

Organism
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Precorrin-2 + NAD+ = sirohydrochlorin + NADH.SAAS annotation

Pathwayi: siroheme biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes sirohydrochlorin from precorrin-2.SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Precorrin-2 dehydrogenase/ferrochelatase (BBR47_12580)
This subpathway is part of the pathway siroheme biosynthesis, which is itself part of Porphyrin-containing compound metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sirohydrochlorin from precorrin-2, the pathway siroheme biosynthesis and in Porphyrin-containing compound metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseSAAS annotation
Biological processPorphyrin biosynthesisSAAS annotation
LigandNADSAAS annotation

Enzyme and pathway databases

BioCyciBBRE358681:G1G2J-1363-MONOMER
UniPathwayiUPA00262; UER00222

Names & Taxonomyi

Protein namesi
Submitted name:
Precorrin-2 dehydrogenase/ferrochelataseImported
Gene namesi
Ordered Locus Names:BBR47_12580Imported
OrganismiBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)Imported
Taxonomic identifieri358681 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus
Proteomesi

Interactioni

Protein-protein interaction databases

STRINGi358681.BBR47_12580

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini118 – 144Sirohm_synth_MInterPro annotationAdd BLAST27

Phylogenomic databases

eggNOGiENOG4108Z73 Bacteria
COG1648 LUCA
HOGENOMiHOG000285944
KOiK02304
OMAiVNMMVKQ
OrthoDBiPOG091H04AY

Family and domain databases

InterProiView protein in InterPro
IPR028161 Met8
IPR036291 NAD(P)-bd_dom_sf
IPR028281 Sirohaem_synthase_central
IPR006367 Sirohaem_synthase_N
PANTHERiPTHR35330 PTHR35330, 1 hit
PfamiView protein in Pfam
PF14824 Sirohm_synth_M, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01470 cysG_Nterm, 1 hit

Sequencei

Sequence statusi: Complete.

C0Z7J2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHYAMMVNL QNKRCLVVGG GQVAERKIGS LLAACADVTV VSPSCTATIL
60 70 80 90 100
EWAHAKKLTV VLRPFTRQDV EEAVLIIAAT SDPAVNLAVY EACRPHQWIN
110 120 130 140 150
IVDRPDLCSF TVPSVVARGD LQIAISTGGN NPGLAKKMRR QLEEWVGPEY
160 170 180 190 200
EDYTLFLGSM RRQILSLSVS EADKRAILAE LLDDRFLQWT KNGETDRRDR
210
EAEALLTMTK E
Length:211
Mass (Da):23,472
Last modified:May 26, 2009 - v1
Checksum:i31B88ADBCB5E6CF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008955 Genomic DNA Translation: BAH42235.1
RefSeqiWP_012684986.1, NC_012491.1

Genome annotation databases

EnsemblBacteriaiBAH42235; BAH42235; BBR47_12580
GeneIDi29258592
KEGGibbe:BBR47_12580

Entry informationi

Entry nameiC0Z7J2_BREBN
AccessioniPrimary (citable) accession number: C0Z7J2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: March 28, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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