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C0Z4E2 (PSD_BREBN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BBR47_06920
OrganismBrevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) [Complete proteome] [HAMAP]
Taxonomic identifier358681 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Paenibacillaceae › Brevibacillus

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000147595
Chain246 – 28035Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000147596

Sites

Site245 – 2462Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2461Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
C0Z4E2 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: E26D40ACB51060BA

FASTA28031,093
        10         20         30         40         50         60 
MGKKLLPGLI HRLPQNAMSR TMGKITATPF SRLAIQRYIK HYQIDTSIIE KPASEYRTLK 

        70         80         90        100        110        120 
EFFSRRLKPA ARPIAPGPDT IVSPVDGTVS QLGDICEGTL IQAKGKDFSV SELLGGSEEE 

       130        140        150        160        170        180 
AKRYYGGKFI TIYLSPRDYH RIHMPVTGDL SSYCYLPGRL YPVNKLGIEN VDRLFARNER 

       190        200        210        220        230        240 
LVTHIKTDSL GDMALVKVGA LFVGSVKVCY NTATTNIKHG RQTHEKIAGT PRYEKGSELG 

       250        260        270        280 
WFEFGSTVIL LLESNELEWA TGVEKGKSLL MGQALATKKA

« Hide

References

[1]"Brevibacillus brevis strain 47, complete genome."
Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W., Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S., Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H. expand/collapse author list , Udaka S., Tanikawa S., Fujita N.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 47 / JCM 6285 / NBRC 100599.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008955 Genomic DNA. Translation: BAH41669.1.
RefSeqYP_002770173.1. NC_012491.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC0Z4E2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7718050.
GenomeReviewsGene locus BBR47_06920 in contig AP008955_GR.
KEGGbbe:BBR47_06920.
PATRIC21231670. VBIBreBre96763_0689.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMASMATVWH.
ProtClustDBCLSK2477636.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BREBN
AccessionPrimary (citable) accession number: C0Z4E2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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