Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

egl-23

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Enzyme and pathway databases

ReactomeiR-CEL-1299344. TWIK-related spinal cord K+ channel (TRESK).

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:egl-23Imported
ORF Names:CELE_Y37A1B.11Imported, Y37A1B.11Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY37A1B.11b; CE43610; WBGene00001190; egl-23.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei58 – 7922HelicalSequence analysisAdd
BLAST
Transmembranei250 – 26819HelicalSequence analysisAdd
BLAST
Transmembranei342 – 36221HelicalSequence analysisAdd
BLAST
Transmembranei369 – 38921HelicalSequence analysisAdd
BLAST
Transmembranei395 – 42127HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiC0Z3L1.

Expressioni

Gene expression databases

BgeeiWBGene00001190.
ExpressionAtlasiC0Z3L1. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y37A1B.11b.

Structurei

3D structure databases

ProteinModelPortaliC0Z3L1.
SMRiC0Z3L1. Positions 185-413.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini215 – 27561Ion_trans_2InterPro annotationAdd
BLAST
Domaini348 – 42174Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00700000104522.
HOGENOMiHOG000022281.
InParanoidiC0Z3L1.
KOiK05323.
OMAiHVNHVLF.
OrthoDBiEOG091G09ZS.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

C0Z3L1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESKTAIFEK YSNETESKEN CLVLGQGLPS KHCSNSSLSS QKMQLDWVKK
60 70 80 90 100
AGKKATPLFV HFLMIVSVGA YAIFGALVMR SLESRTVTSI EKKTDVHRRH
110 120 130 140 150
VNLTNFQHPP TPITLEQRHR RRRRHNETAL EDHLSEKLSR EKRAAAHIMR
160 170 180 190 200
SRKCVISVIK KMSSMECSFD TLDEKLVKAL DECYHVAVEH NTHVNHVLFT
210 220 230 240 250
NSKEEVESVG EEAEEDVSEW SFMDSLLFAF TVITTIGYGN VAPRTFGGRL
260 270 280 290 300
FVIGYGLIGI PFTLLAIADL GKFISEMMVE AKSFCRKTWK KLKKAWNPNF
310 320 330 340 350
IRAKDLSNTD IEEKILDNEK IENEPETSEV SEEEDDLTET EATSLFILFL
360 370 380 390 400
VYIAFGGFML AAYEPDMDFF KAVYFNFVTL TSIGLGDIVP RSETYMLITI
410 420 430 440 450
VYIAIGLALT TIAIEIAADA LKKLHYFGRK IENVGNVAIW FGGKKITMKA
460 470 480 490 500
LVKNLGDQFN LPTTVVKNLN LDHFVDQAIK VEEGEIETLR PPPYEPPSDR
510 520 530 540 550
FEAEFADEPE CEWIRDPTPT PPPSPQPVYR LPSPKPVTPE PLPSPTITDV
560 570 580 590 600
SLAIATPSPE ESDDDQELIL PSPEPSPVRE PTPPPPPREP TPREPTPEPE
610 620 630 640 650
PVREPTPPPP PPAKPRPLTA AEIAAQKRKA YSEEAWRRYQ EYQKQWKKFR
660 670 680 690 700
QTQKTPAPSG ASTSGASTSK PSGTSPESGA GVCTGPSTRS QSITSVASGK
710 720
TSRSATPESK KSSHLSGSSR RESGGK
Length:726
Mass (Da):80,857
Last modified:May 26, 2009 - v1
Checksum:i25D352F713DCBA1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAX65085.1.
RefSeqiNP_001255775.1. NM_001268846.1.
UniGeneiCel.12114.

Genome annotation databases

EnsemblMetazoaiY37A1B.11b; Y37A1B.11b; WBGene00001190.
GeneIDi178358.
KEGGicel:CELE_Y37A1B.11.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAX65085.1.
RefSeqiNP_001255775.1. NM_001268846.1.
UniGeneiCel.12114.

3D structure databases

ProteinModelPortaliC0Z3L1.
SMRiC0Z3L1. Positions 185-413.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.Y37A1B.11b.

Proteomic databases

PaxDbiC0Z3L1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY37A1B.11b; Y37A1B.11b; WBGene00001190.
GeneIDi178358.
KEGGicel:CELE_Y37A1B.11.

Organism-specific databases

CTDi178358.
WormBaseiY37A1B.11b; CE43610; WBGene00001190; egl-23.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00700000104522.
HOGENOMiHOG000022281.
InParanoidiC0Z3L1.
KOiK05323.
OMAiHVNHVLF.
OrthoDBiEOG091G09ZS.

Enzyme and pathway databases

ReactomeiR-CEL-1299344. TWIK-related spinal cord K+ channel (TRESK).

Gene expression databases

BgeeiWBGene00001190.
ExpressionAtlasiC0Z3L1. baseline.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Entry informationi

Entry nameiC0Z3L1_CAEEL
AccessioniPrimary (citable) accession number: C0Z3L1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: September 7, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.