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C0Z0P8 (C0Z0P8_LACRE) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP-Rule MF_00038

EC=2.7.8.13 HAMAP-Rule MF_00038
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferase HAMAP-Rule MF_00038
Gene names
Name:mraY HAMAP-Rule MF_00038 EMBL EEI08559.1
ORF Names:HMPREF0535_1613 EMBL EEI08559.1
OrganismLactobacillus reuteri MM2-3 EMBL EEI08559.1
Taxonomic identifier585517 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP-Rule MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP-Rule MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00038

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily. HAMAP-Rule MF_00038

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EEI08559.1

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane37 – 5721Helical; By similarity HAMAP-Rule MF_00038
Transmembrane61 – 8121Helical; By similarity HAMAP-Rule MF_00038
Transmembrane98 – 11821Helical; By similarity HAMAP-Rule MF_00038
Transmembrane120 – 14021Helical; By similarity HAMAP-Rule MF_00038
Transmembrane153 – 17321Helical; By similarity HAMAP-Rule MF_00038
Transmembrane176 – 19621Helical; By similarity HAMAP-Rule MF_00038
Transmembrane205 – 22723Helical; By similarity HAMAP-Rule MF_00038
Transmembrane231 – 25323Helical; By similarity HAMAP-Rule MF_00038
Transmembrane282 – 30221Helical; By similarity HAMAP-Rule MF_00038

Sequences

Sequence LengthMass (Da)Tools
C0Z0P8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 702E9CDF428CEAA3

FASTA30333,569
        10         20         30         40         50         60 
MPSLIKYFRA KKEGQQIRKE GPTWHAKKAG TPTMGGLLFI FSAVVTILWV AAWQGLITNT 

        70         80         90        100        110        120 
LWALLFVLVV YGLIGMWDDS IKIFHHQNEG FKPWQKALCQ VLAAMVFTVI YQHEGFQMGF 

       130        140        150        160        170        180 
GTTQIGWLYG LFIIFWIVGF SNAVNLTDGL DGLVSGLSII SFAAYLIIAL VNLNQPGYPE 

       190        200        210        220        230        240 
IALFCLAMIG TLLGFFPYNH KPAKIFMGDM GSLAIGASLA AVSLLLHHEW SLLVIGIVYV 

       250        260        270        280        290        300 
CETASVILQV ASFKTTGKRI FKMTPIHHHF EMSGWSEWKI DIVFWLVGLV AAIIAVTTIL 


LVG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ACLB01000090 Genomic DNA. Translation: EEI08559.1.

3D structure databases

ProteinModelPortalC0Z0P8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEEI08559; EEI08559; HMPREF0535_1613.
PATRIC37024688. VBILacReu127513_1232.

Phylogenomic databases

OrthoDBEOG69GZPZ.

Enzyme and pathway databases

UniPathwayUPA00219.

Family and domain databases

HAMAPMF_00038. MraY.
InterProIPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERPTHR22926. PTHR22926. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. mraY. 1 hit.
PROSITEPS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0Z0P8_LACRE
AccessionPrimary (citable) accession number: C0Z0P8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)