C0X5E9 (C0X5E9_ENTFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Shikimate 5-dehydrogenase EMBL EEI11767.1

Gene names

Name:	aroE EMBL EEI11767.1
ORF Names:	HMPREF0348_1734 EMBL EEI11767.1

Organism

Enterococcus faecalis TX0104 EMBL EEI11767.1

Taxonomic identifier

491074 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Enterococcaceae › Enterococcus

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. SAAS SAAS011342

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342
Ligand	NADP SAAS SAAS011342
Molecular function	Oxidoreductase RuleBase RU004037 SAAS SAAS011342
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C0X5E9 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 1DC0DBA75BCAAA22	FASTA	288	31,442
	10 20 30 40 50 60 MKEITGATRL AGLFAKPSQH SISPLIHNTA FQNLGVDARY LAFDVGQETL PQAIEAIRTF 70 80 90 100 110 120 HMLGANLSMP NKVAAVSYMD ELSPTAQLVG AINTIVNKDG KLYGDSTDGT GFMWSLKEKK 130 140 150 160 170 180 VDVFQNKMTI LGTGGAALSI IAQAALDGVK EIAVYNRKSA GFNDSQKKLA NFTERTNCVI 190 200 210 220 230 240 HLNDLADTEK LAKDVAESVL LVNATSVGMH PHAHSSPIEN YAMIQPKLFV YDAIYNPRET 250 260 270 280 QLLKEARLRG AETSNGLDML LYQGAAAFEQ WTGQKMPVSV VKRKIENR

References

[1]

Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L., Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G., Francisco L., Fu Q., Gubbala S., Hale W., Han Y. , Hemphill L., Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A., Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R., Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R., Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P., Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y., Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L., Zhou C., Zhu D., Muzny D., Worley K., Gibbs R. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: TX0104 EMBL EEI11767.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACGL01000114 Genomic DNA. Translation: EEI11767.1.
3D structure databases
ProteinModelPortal	C0X5E9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	26761131. VBIEntFae109560_0178.
Phylogenomic databases
OMA	AWEVESK.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR011342. Shikimate_DH. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
Pfam	PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00507. AroE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C0X5E9_ENTFA

Accession

Primary (citable) accession number: C0X5E9

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)