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C0RJK3

- C0RJK3_BRUMB

UniProt

C0RJK3 - C0RJK3_BRUMB

Protein

Elongation factor Tu

Gene

tuf

Organism
Brucella melitensis biotype 2 (strain ATCC 23457)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBMEL546272:GJOX-1244-MONOMER.
    BMEL546272:GJOX-1260-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:BMEA_A1280Imported, BMEA_A1296Imported
    OrganismiBrucella melitensis biotype 2 (strain ATCC 23457)Imported
    Taxonomic identifieri546272 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000001748: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi546272.BMEA_A1296.

    Structurei

    3D structure databases

    SMRiC0RJK3. Positions 2-390.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C0RJK3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKSKFERTK PHVNIGTIGH VDHGKTSLTA AITKFFGEFK AYDQIDAAPE    50
    ERARGITIST AHVEYETANR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    VSAADGPMPQ TREHILLARQ VGVPAIVVFL NKCDQVDDAE LLELVELEVR 150
    ELLSKYEFPG DEIPIIKGSA LAALEDSSKE LGEDAIRNLM DAVDSYIPTP 200
    ERPIDQPFLM PIEDVFSISG RGTVVTGRVE RGIVKVGEEV EIVGIKATTK 250
    TTVTGVEMFR KLLDQGQAGD NIGALIRGVG REDVERGQVL CKPGSVKPHT 300
    KFKAEAYILT KDEGGRHTPF FTNYRPQFYF RTTDVTGVVT LPAGTEMVMP 350
    GDNVAMDVTL IVPIAMEEKL RFAIREGGRT VGAGIVSSII E 391
    Length:391
    Mass (Da):42,605
    Last modified:May 5, 2009 - v1
    Checksum:iED4CDF37183A900E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001488 Genomic DNA. Translation: ACO01011.1.
    CP001488 Genomic DNA. Translation: ACO01026.1.
    RefSeqiYP_002732965.1. NC_012441.1.
    YP_002732980.1. NC_012441.1.

    Genome annotation databases

    EnsemblBacteriaiACO01011; ACO01011; BMEA_A1280.
    ACO01026; ACO01026; BMEA_A1296.
    GeneIDi7677024.
    7677161.
    KEGGibmi:BMEA_A1280.
    bmi:BMEA_A1296.
    PATRICi17838313. VBIBruMel14466_1300.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001488 Genomic DNA. Translation: ACO01011.1 .
    CP001488 Genomic DNA. Translation: ACO01026.1 .
    RefSeqi YP_002732965.1. NC_012441.1.
    YP_002732980.1. NC_012441.1.

    3D structure databases

    SMRi C0RJK3. Positions 2-390.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 546272.BMEA_A1296.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO01011 ; ACO01011 ; BMEA_A1280 .
    ACO01026 ; ACO01026 ; BMEA_A1296 .
    GeneIDi 7677024.
    7677161.
    KEGGi bmi:BMEA_A1280.
    bmi:BMEA_A1296.
    PATRICi 17838313. VBIBruMel14466_1300.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci BMEL546272:GJOX-1244-MONOMER.
    BMEL546272:GJOX-1260-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project."
      Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C.
      , Tapia R., Han C., Detter J.C., Bruce D., Brettin T.S.
      Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23457Imported.
    2. "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project."
      Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C.
      , Tapia R., Han c., Detter J.C., Bruce D., Brettin T.S.
      Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: ATCC 23457Imported.

    Entry informationi

    Entry nameiC0RJK3_BRUMB
    AccessioniPrimary (citable) accession number: C0RJK3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 5, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3