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C0RH03

- G6PI_BRUMB

UniProt

C0RH03 - G6PI_BRUMB

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Brucella melitensis biotype 2 (strain ATCC 23457)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei384 – 3841UniRule annotation
    Active sitei513 – 5131UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciBMEL546272:GJOX-307-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:BMEA_A0320
    OrganismiBrucella melitensis biotype 2 (strain ATCC 23457)
    Taxonomic identifieri546272 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000001748: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 549549Glucose-6-phosphate isomerasePRO_1000135518Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi546272.BMEA_A0320.

    Structurei

    3D structure databases

    ProteinModelPortaliC0RH03.
    SMRiC0RH03. Positions 13-549.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C0RH03-1 [UniParc]FASTAAdd to Basket

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    MARDATKLEA TVAKLKKHWA ESAPRDMRAA FSADPGRFGR YSLCLDDLLF    50
    DWSKCRVNDE TMALLKELAV AADVEGRRAA MFAGEHINNT EDRAVLHVAL 100
    RDTSSKEVLV DGHNVLPDVK HVLDRMAAFA DGIRSGALKG ATGRKITDIV 150
    NIGIGGSDLG PVMATLALAP YHDEPRAHFV SNIDGAHIAD TLSPLDPAST 200
    LIIVASKTFT TIETMTNAQT ARKWVADTLG EAAVGAHFAA VSTALDKVAA 250
    FGIPEDRVFG FWDWVGGRYS VWSAIGLPVM IAVGPDNFRK FLAGAHAMDV 300
    HFRDAPLEKN LPVMLGLIGY WHRAICGYGS RAIIPYDQRL SRLPAYLQQL 350
    DMESNGKSVT LDGKPVSGPT GPVVWGEPGT NGQHAFFQLL HQGTDTIPLE 400
    FIVAAKGHEP TLDHQHEMLM ANCLAQSEAL MKGRTLDEAR AQLQAKNLPA 450
    SQVERIAPHR VFSGNRPSLT LIHDMLDPYT LGRLIALYEH RVFVEAQIFG 500
    INAFDQWGVE LGKELATELL PVVSGKEGAS GRDASTQGLV AHLHARRKA 549
    Length:549
    Mass (Da):59,642
    Last modified:May 5, 2009 - v1
    Checksum:iB2EFDDCE8392C968
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001488 Genomic DNA. Translation: ACO00111.1.
    RefSeqiYP_002732065.1. NC_012441.1.

    Genome annotation databases

    EnsemblBacteriaiACO00111; ACO00111; BMEA_A0320.
    GeneIDi7678026.
    KEGGibmi:BMEA_A0320.
    PATRICi17836355. VBIBruMel14466_0336.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001488 Genomic DNA. Translation: ACO00111.1 .
    RefSeqi YP_002732065.1. NC_012441.1.

    3D structure databases

    ProteinModelPortali C0RH03.
    SMRi C0RH03. Positions 13-549.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 546272.BMEA_A0320.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO00111 ; ACO00111 ; BMEA_A0320 .
    GeneIDi 7678026.
    KEGGi bmi:BMEA_A0320.
    PATRICi 17836355. VBIBruMel14466_0336.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci BMEL546272:GJOX-307-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project."
      Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C.
      , Tapia R., Han C., Detter J.C., Bruce D., Brettin T.S.
      Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23457.

    Entry informationi

    Entry nameiG6PI_BRUMB
    AccessioniPrimary (citable) accession number: C0RH03
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3