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Protein

Putative pyruvate, phosphate dikinase regulatory protein

Gene

BMEA_A2129

Organism
Brucella melitensis biotype 2 (strain ATCC 23457)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

Catalytic activityi

ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate.UniRule annotation
[Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi153 – 1608ADPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

Nucleotide-binding

Enzyme and pathway databases

BioCyciBMEL546272:GJOX-2073-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pyruvate, phosphate dikinase regulatory proteinUniRule annotation (EC:2.7.11.32UniRule annotation, EC:2.7.4.27UniRule annotation)
Short name:
PPDK regulatory proteinUniRule annotation
Gene namesi
Ordered Locus Names:BMEA_A2129
OrganismiBrucella melitensis biotype 2 (strain ATCC 23457)
Taxonomic identifieri546272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000001748 Componenti: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Putative pyruvate, phosphate dikinase regulatory proteinPRO_1000149701Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218052.
KOiK09773.
OMAiYAQCEFE.

Family and domain databases

HAMAPiMF_00921. PDRP. 1 hit.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026565. PPDK_reg.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0RFV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRPLSYFHL HLISDATGET LLAAGRAAAA QYANARAIEH IYPLIRTEKQ
60 70 80 90 100
LRKVLEGIDA EPGIVLYTVV DQKLAAIIDE SCADMGVPSV SVLEPVLNTF
110 120 130 140 150
QSYLGAPAHR RASAQHVLNA DYFRRIDALN FMMEHDDGQL PLDIEEADVI
160 170 180 190 200
IVGISRTSKT PTSIYLANRG IKAANVPLVL GIPVPEILFA AKRPLIVGLV
210 220 230 240 250
ATAERISQIR QNRPIGNIPS LDTGLYTDRV SISEELAYAR NLCNRHGWPI
260 270
IDVSRRSIEE TAAAILALLR NGKKEGSSS
Length:279
Mass (Da):30,481
Last modified:May 5, 2009 - v1
Checksum:i425660E8BA136FA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001488 Genomic DNA. Translation: ACO01777.1.
RefSeqiWP_004686215.1. NC_012441.1.

Genome annotation databases

EnsemblBacteriaiACO01777; ACO01777; BMEA_A2129.
KEGGibmi:BMEA_A2129.
PATRICi17840060. VBIBruMel14466_2141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001488 Genomic DNA. Translation: ACO01777.1.
RefSeqiWP_004686215.1. NC_012441.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO01777; ACO01777; BMEA_A2129.
KEGGibmi:BMEA_A2129.
PATRICi17840060. VBIBruMel14466_2141.

Phylogenomic databases

HOGENOMiHOG000218052.
KOiK09773.
OMAiYAQCEFE.

Enzyme and pathway databases

BioCyciBMEL546272:GJOX-2073-MONOMER.

Family and domain databases

HAMAPiMF_00921. PDRP. 1 hit.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026565. PPDK_reg.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPDRP_BRUMB
AccessioniPrimary (citable) accession number: C0RFV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: September 7, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.