C0R4N8 (C0R4N8_WOLWR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Coproporphyrinogen III oxidase EMBL ACN95880.1

Gene names

Ordered Locus Names:

WRi_011940

Organism

Wolbachia sp. subsp. Drosophila simulans (strain wRi) [Complete proteome] [HAMAP]

Taxonomic identifier

66084 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. SAAS SAAS018375
Catalytic activity	Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. SAAS SAAS018375
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. SAAS SAAS018375
Subunit structure	Homodimer By similarity. SAAS SAAS018375

Ontologies

Keywords
Biological process	Porphyrin biosynthesis SAAS SAAS018375
Molecular function	Oxidoreductase SAAS SAAS018375
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C0R4N8 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 834D06465F4C6669	FASTA	274	31,713
	10 20 30 40 50 60 MEKQKTQAFK WFCALRDKII ESFLLIEKQS SAEPKIEKRK WDRPGGGGGE STIIFGNVFE 70 80 90 100 110 120 KVGVNVSKVH GKFADSAINE IPGASESNGE FWASGISLVS HMQSPLIPAA HMNTRLIYTS 130 140 150 160 170 180 KQWFGGGMDF TPIYRNEEDC KYIHESIKMI CDRFDTGYYP KFKEQCDNYF FLQHRKEPRG 190 200 210 220 230 240 IGGIFYDNLS SGNWENDFEF TKAVGEAFLE IYLHIIRKHI QKSWTKEQRE NQLIKRGRYV 250 260 270 EFNLLYDRGT RFGLMTDGNP DAIMMSMPPL VKWL

References

[1]

"The mosaic genome structure of the Wolbachia wRi strain infecting Drosophila simulans." Klasson L., Westberg J., Sapountzis P., Naeslund K., Lutnaes Y., Darby A.C., Veneti Z., Chen L., Braig H.R., Garrett R., Bourtzis K., Andersson S.G. Proc. Natl. Acad. Sci. U.S.A. 106:5725-5730(2009) [PubMed: 19307581] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001391 Genomic DNA. Translation: ACN95880.1.
RefSeq	YP_002727671.1. NC_012416.1.
3D structure databases
ProteinModelPortal	C0R4N8.
ModBase	Search...
Protein-protein interaction databases
STRING	C0R4N8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBWOLT00000001622; EBWOLP00000001472; EBWOLG00000001622.
GeneID	7669906.
GenomeReviews	Gene locus WRi_011940 in contig CP001391_GR.
KEGG	wri:WRi_011940.
PATRIC	24036734. VBIWolSp98304_1356.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000031207.
OMA	GKEPVWW.
ProtClustDB	PRK05330.
Family and domain databases
InterPro	IPR001260. Coprogen_oxidase_aer. IPR018375. Coprogen_oxidase_CS. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KO	K00228.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
SUPFAM	SSF102886. Coprogen_oxidas. 1 hit.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C0R4N8_WOLWR

Accession

Primary (citable) accession number: C0R4N8

Entry history

Integrated into UniProtKB/TrEMBL:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)