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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Wolbachia sp. subsp. Drosophila simulans (strain wRi)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (pgm)
  4. Enolase (eno)
  5. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei117SubstrateUniRule annotation1
Binding sitei150SubstrateUniRule annotation1
Binding sitei200ATPUniRule annotation1
Binding sitei321ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi351 – 354ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:WRi_011430
OrganismiWolbachia sp. subsp. Drosophila simulans (strain wRi)
Taxonomic identifieri66084 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
Proteomesi
  • UP000001293 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001928601 – 398Phosphoglycerate kinaseAdd BLAST398

Proteomic databases

PRIDEiC0R4J5

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliC0R4J5
SMRiC0R4J5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG

Family and domain databases

Gene3Di3.40.50.1260, 3 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

C0R4J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIPSIENCD LHNKAVLLRV DFNVPIKDGE IRDVTRILRA LPTIQYLVNA
60 70 80 90 100
SAKIIIISHF GRPKARDNNL SLKNVIDTLS QLLNKKVKFI DDCVGEKVQK
110 120 130 140 150
AVSAMDAGDI ILLENLRFYE GEKENDANFA RQLASLADIY VNDAFSCSHR
160 170 180 190 200
AHASISRITE FLPSYAGFCL QDELKYLEKA VSFKAKPITA IVGGAKISTK
210 220 230 240 250
IKVLMKLTEK VDYLVLGGAI ANNFLSFSKV NIGKSFFQNG VDDLLHNIVE
260 270 280 290 300
TANKNNCKIV VPEDVLVAVN SDYSTSISRK TESILDGDII LDIGSQTLST
310 320 330 340 350
ISSIIASSKT LLWNGPIGVF EHSAFASGTI GVMKIVSDLT HKGKLTSIIG
360 370 380 390
GGDSLSAISA AGLTDKDFTY VSTGGGAFLD WLSGDEMPGV AALQKRLD
Length:398
Mass (Da):43,118
Last modified:May 5, 2009 - v1
Checksum:iA1ADAF4BAF9292AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001391 Genomic DNA Translation: ACN95837.1
RefSeqiWP_006280509.1, NZ_MKIF01000089.1

Genome annotation databases

EnsemblBacteriaiACN95837; ACN95837; WRi_011430
KEGGiwri:WRi_011430

Similar proteinsi

Entry informationi

Entry nameiPGK_WOLWR
AccessioniPrimary (citable) accession number: C0R4J5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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