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Protein

UDP-glucose 6-dehydrogenase

Gene

WRi_005820

Organism
Wolbachia sp. subsp. Drosophila simulans (strain wRi)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei30NADUniRule annotation1
Binding sitei35NADUniRule annotation1
Binding sitei86NADUniRule annotation1
Binding sitei121NAD; via amide nitrogenUniRule annotation1
Active sitei260NucleophileUniRule annotation1
Binding sitei263NADUniRule annotation1
Binding sitei327NADUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose 6-dehydrogenaseUniRule annotation (EC:1.1.1.22UniRule annotation)
Gene namesi
Ordered Locus Names:WRi_005820Imported, WRi_010480Imported
OrganismiWolbachia sp. subsp. Drosophila simulans (strain wRi)Imported
Taxonomic identifieri66084 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
Proteomesi
  • UP000001293 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliC0R367
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini313 – 414UDPG_MGDP_dh_CInterPro annotationAdd BLAST102

Sequence similaritiesi

Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000153773
KOiK00012
OMAiANVCFIF

Family and domain databases

InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR036291 NAD(P)-bd_dom_sf
IPR017476 UDP-Glc/GDP-Man
IPR014027 UDP-Glc/GDP-Man_DH_C
IPR036220 UDP-Glc/GDP-Man_DH_C_sf
IPR014026 UDP-Glc/GDP-Man_DH_dimer
IPR001732 UDP-Glc/GDP-Man_DH_N
IPR028357 UDPglc_DH_bac
PfamiView protein in Pfam
PF00984 UDPG_MGDP_dh, 1 hit
PF03720 UDPG_MGDP_dh_C, 1 hit
PF03721 UDPG_MGDP_dh_N, 1 hit
PIRSFiPIRSF500134 UDPglc_DH_bac, 1 hit
PIRSF000124 UDPglc_GDPman_dh, 1 hit
SMARTiView protein in SMART
SM00984 UDPG_MGDP_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
SSF52413 SSF52413, 1 hit
TIGRFAMsiTIGR03026 NDP-sugDHase, 1 hit

Sequencei

Sequence statusi: Complete.

C0R367-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYITIIGIGY VGLVSCAMLS EQGHNVDCID INTKKIELLK LGKIPIYEPG
60 70 80 90 100
LADYLENNIK LQRIRFFDSY SQINPNTEVV FVTVDTPSDS LGNANLQNVY
110 120 130 140 150
NAVSEVSERV NQDCLIVIKS TVPPGTAENI YNYLSNKGYN FDLGVNPEFL
160 170 180 190 200
KQGSAVSDFL YPDRIIIGVK TKLARAKLEV IYRSFIDKNI PLIVTDTVTA
210 220 230 240 250
EMIKYASNAF LATKVAFINE MAGLCELLGA DIDLLANSMG MDHRIGKEFL
260 270 280 290 300
KAGPGFGGSC FPKDLSALIR LAEDHNVKLQ ILNSVKESNY NHITNIAKKV
310 320 330 340 350
EYVLNGVQNK KIAIWGLTFK SGTDDVRNSP AIDIAQLLVN NKAKITAYDP
360 370 380 390 400
MGMDNARQVL KDIEYADNAI GAARDAEALL LLTEWKEFKN QDFASLKSIM
410 420 430
AAPNVFDFRN LLDSELLLRY GYHVYSLGKK SIYKV
Length:435
Mass (Da):48,327
Last modified:May 5, 2009 - v1
Checksum:i18165E39C9F50802
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001391 Genomic DNA Translation: ACN95359.1
CP001391 Genomic DNA Translation: ACN95753.1
RefSeqiWP_006280072.1, NZ_MKIF01000142.1

Genome annotation databases

EnsemblBacteriaiACN95359; ACN95359; WRi_005820
ACN95753; ACN95753; WRi_010480
GeneIDi29555204
KEGGiwri:WRi_005820
wri:WRi_010480

Similar proteinsi

Entry informationi

Entry nameiC0R367_WOLWR
AccessioniPrimary (citable) accession number: C0R367
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health