C0QY51 (GCP_BRAHW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BHWA1_00427

Organism

Brachyspira hyodysenteriae (strain ATCC 49526 / WA1) [Complete proteome] [HAMAP]

Taxonomic identifier

565034 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Brachyspiraceae › Brachyspira

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000184953

Sequences

	Sequence		Length	Mass (Da)
	C0QY51 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: F85ABEF60CC4BE8D	FASTA	340	37,180
	10 20 30 40 50 60 MKILGIDTSC DDTSAAIVED GKNVLSSVLS SSIDAHKEFQ GVVPEIAARK HLEAILYVID 70 80 90 100 110 120 KALKDANTTL DDIDLFAVTN RPGLLGSLLV GVASAKSLAF SLNKPLLALD HIAAHIYSPH 130 140 150 160 170 180 LTNDIEFPYI ALVVSGGHTI ITEVHDYGEY KVVGTTLDDA VGEAYDKVSK FLNLGYPGGP 190 200 210 220 230 240 IIDRLAKEGN KEAIKYPIVL LNGIDEFNFS YSGLKTACVY STKKYLKEGY EATNENIAAA 250 260 270 280 290 300 FQISAIEPLY IKTLKYAEKS GIKRVTLSGG VACNSYLRDR FGNSKDFECY LPALKYTTDN 310 320 330 340 AAMVAGLAYH MKDKQNFADY NLDCFSRVLN KKYNKNKSAK

References

[1]

"Genome sequence of the pathogenic intestinal spirochete Brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine." Bellgard M.I., Wanchanthuek P., La T., Ryan K., Moolhuijzen P., Albertyn Z., Shaban B., Motro Y., Dunn D.S., Schibeci D., Hunter A., Barrero R., Phillips N.D., Hampson D.J. PLoS ONE 4:E4641-E4641(2009) [PubMed: 19262690] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49526 / WA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001357 Genomic DNA. Translation: ACN82923.1.
RefSeq	YP_002720596.1. NC_012225.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C0QY51.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7665533.
GenomeReviews	Gene locus BHWA1_00427 in contig CP001357_GR.
KEGG	bhy:BHWA1_00427.
PATRIC	21178941. VBIBraHyo62857_0417.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MEVIGQT.
ProtClustDB	CLSK2809465.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BRAHW

Accession

Primary (citable) accession number: C0QY51

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 5, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program