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C0QV47

- GPMA_BRAHW

UniProt

C0QV47 - GPMA_BRAHW

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Protein
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Gene
gpmA, BHWA1_01885
Organism
Brachyspira hyodysenteriae (strain ATCC 49526 / WA1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91Tele-phosphohistidine intermediate By similarity
Binding sitei15 – 1512-phospho-D-glycerate By similarity
Binding sitei60 – 6012-phospho-D-glycerate By similarity
Binding sitei98 – 9812-phospho-D-glycerate By similarity
Active sitei182 – 1821 By similarity
Binding sitei184 – 18412-phospho-D-glycerate By similarity

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Glycolysis

Enzyme and pathway databases

BioCyciBHYO565034:GJI7-1873-MONOMER.
UniPathwayiUPA00109; UER00186.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (EC:5.4.2.11)
Short name:
BPG-dependent PGAM
Short name:
PGAM
Short name:
Phosphoglyceromutase
Short name:
dPGM
Gene namesi
Name:gpmA
Ordered Locus Names:BHWA1_01885
OrganismiBrachyspira hyodysenteriae (strain ATCC 49526 / WA1)
Taxonomic identifieri565034 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBrachyspiraceaeBrachyspira
ProteomesiUP000001803: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2482482,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation
PRO_1000149505Add
BLAST

Proteomic databases

PRIDEiC0QV47.

Interactioni

Protein-protein interaction databases

STRINGi565034.BHWA1_01885.

Structurei

3D structure databases

ProteinModelPortaliC0QV47.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 2222-phospho-D-glycerate binding By similarity
Regioni87 – 9042-phospho-D-glycerate binding By similarity
Regioni114 – 11522-phospho-D-glycerate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0588.
HOGENOMiHOG000221682.
KOiK01834.
OMAiIKEWRRS.
OrthoDBiEOG6C8N1H.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0QV47-1 [UniParc]FASTAAdd to Basket

« Hide

MTKVVLIRHG ESVWNKENLF TGWADVTLSE KGIEEAKAGG AELKKAGFTF    50
DKAYTSTLTR AIKTLNLVLE EMGLLWIPVD KCWQLNERHY GALQGLNKSQ 100
TAEKYGEDQV KIWRRSYDTP PPALEKSDER YPGHDPRYKN LSEKELPLTE 150
CLKDTVARVV PFWENVILPD IKAGKKIIIA AHGNSLRALV KYLDNISDAD 200
ITELNIPTGM PLVYELDDNF KAVNKQYLGD PEAVKKAMEA VANQGKKK 248
Length:248
Mass (Da):27,945
Last modified:May 5, 2009 - v1
Checksum:i40DA5C6D2DF17791
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001357 Genomic DNA. Translation: ACN84348.1.
RefSeqiWP_012671388.1. NC_012225.1.
YP_002722052.1. NC_012225.1.

Genome annotation databases

EnsemblBacteriaiACN84348; ACN84348; BHWA1_01885.
GeneIDi7666977.
KEGGibhy:BHWA1_01885.
PATRICi21181827. VBIBraHyo62857_1837.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001357 Genomic DNA. Translation: ACN84348.1 .
RefSeqi WP_012671388.1. NC_012225.1.
YP_002722052.1. NC_012225.1.

3D structure databases

ProteinModelPortali C0QV47.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 565034.BHWA1_01885.

Proteomic databases

PRIDEi C0QV47.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACN84348 ; ACN84348 ; BHWA1_01885 .
GeneIDi 7666977.
KEGGi bhy:BHWA1_01885.
PATRICi 21181827. VBIBraHyo62857_1837.

Phylogenomic databases

eggNOGi COG0588.
HOGENOMi HOG000221682.
KOi K01834.
OMAi IKEWRRS.
OrthoDBi EOG6C8N1H.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00186 .
BioCyci BHYO565034:GJI7-1873-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
HAMAPi MF_01039. PGAM_GpmA.
InterProi IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view ]
PANTHERi PTHR11931. PTHR11931. 1 hit.
Pfami PF00300. His_Phos_1. 1 hit.
[Graphical view ]
SMARTi SM00855. PGAM. 1 hit.
[Graphical view ]
SUPFAMi SSF53254. SSF53254. 1 hit.
TIGRFAMsi TIGR01258. pgm_1. 1 hit.
PROSITEi PS00175. PG_MUTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the pathogenic intestinal spirochete Brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine."
    Bellgard M.I., Wanchanthuek P., La T., Ryan K., Moolhuijzen P., Albertyn Z., Shaban B., Motro Y., Dunn D.S., Schibeci D., Hunter A., Barrero R., Phillips N.D., Hampson D.J.
    PLoS ONE 4:E4641-E4641(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49526 / WA1.

Entry informationi

Entry nameiGPMA_BRAHW
AccessioniPrimary (citable) accession number: C0QV47
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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