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Protein

Thymidine kinase

Gene

BHWA1_01863

Organism
Brachyspira hyodysenteriae (strain ATCC 49526 / WA1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:BHWA1_01863Imported
OrganismiBrachyspira hyodysenteriae (strain ATCC 49526 / WA1)Imported
Taxonomic identifieri565034 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesBrachyspiralesBrachyspiraceaeBrachyspira
Proteomesi
  • UP000001803 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi565034.BHWA1_01863.

Structurei

3D structure databases

ProteinModelPortaliC0QV25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107VXR. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000096068.
KOiK00857.
OMAiIYSKRIV.
OrthoDBiPOG091H0659.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

C0QV25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFAGKSKYLI KTLDYLLLEN KNIKILFIYP AISFRGYFCR DKNVYLDKRI
60 70 80 90 100
DIITEEEIEN NIGKDVENIY NYIARYDIVG IDEFCFLNDT SIFIQLIKTC
110 120 130 140 150
TQRNCKTNFC IASLDMDYKR NYWESVSALI EEDLIDIHTK VFGKCDCGRK
160 170 180
GIYSKRIVKD VDRVVIGDDI YKCVCRYCYE GEDEVKFNL
Length:189
Mass (Da):22,310
Last modified:May 5, 2009 - v1
Checksum:i901D92433A6EE8A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001357 Genomic DNA. Translation: ACN84326.1.

Genome annotation databases

EnsemblBacteriaiACN84326; ACN84326; BHWA1_01863.
KEGGibhy:BHWA1_01863.
PATRICi21181783. VBIBraHyo62857_1815.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001357 Genomic DNA. Translation: ACN84326.1.

3D structure databases

ProteinModelPortaliC0QV25.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi565034.BHWA1_01863.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACN84326; ACN84326; BHWA1_01863.
KEGGibhy:BHWA1_01863.
PATRICi21181783. VBIBraHyo62857_1815.

Phylogenomic databases

eggNOGiENOG4107VXR. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000096068.
KOiK00857.
OMAiIYSKRIV.
OrthoDBiPOG091H0659.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC0QV25_BRAHW
AccessioniPrimary (citable) accession number: C0QV25
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: March 15, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.