C0QUS3 (C0QUS3_PERMH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dethiobiotin synthase EMBL ACO03478.1
EC=6.3.3.3 EMBL ACO03478.1

Gene names

Name:	bioD EMBL ACO03478.1
Ordered Locus Names:	PERMA_0649

Organism

Persephonella marina (strain DSM 14350 / EX-H1) [Complete proteome] [HAMAP]

Taxonomic identifier

123214 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Hydrogenothermaceae › Persephonella

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472 EMBL ACO03478.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C0QUS3 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 3922EF24060C007F	FASTA	225	24,986
	10 20 30 40 50 60 MNKTVFITAT DTGVGKTIVS AALASILRSQ GKNVGYFKPV ETGCDPLCPD ALLLSKITGQ 70 80 90 100 110 120 HYDEVVLYRF KEAVAPYVAE REEGKHIKID LISEKIKHLQ QIYEYLIIEG AGGVAVPITY 130 140 150 160 170 180 HRDKIYTYLD LISDLDLGAV VVSRASLGTI NHTYLTVESM KRRNIRIKGI ILNERSESPS 190 200 210 220 LAEQTNPKII EKMTGVPVIT ICEKGKIPLL ICIERLKAKI EEIFG

References

[1]

"Complete and draft genome sequences of six members of the Aquificales." Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A. J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001230 Genomic DNA. Translation: ACO03478.1.
RefSeq	YP_002730438.1. NC_012440.1.
3D structure databases
ProteinModelPortal	C0QUS3.
ModBase	Search...
Protein-protein interaction databases
STRING	C0QUS3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7674384.
GenomeReviews	Gene locus PERMA_0649 in contig CP001230_GR.
KEGG	pmx:PERMA_0649.
PATRIC	22914765. VBIPerMar119911_0692.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ANCVDPN.
ProtClustDB	CLSK2299428.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C0QUS3_PERMH

Accession

Primary (citable) accession number: C0QUS3

Entry history

Integrated into UniProtKB/TrEMBL:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)