C0QTU9 (C0QTU9_PERMH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate dehydratase HAMAP MF_00214
Short name=3-dehydroquinase HAMAP MF_00214
EC=4.2.1.10 HAMAP MF_00214

Alternative name(s):
Type I DHQase HAMAP MF_00214

Gene names

Name:	aroD HAMAP MF_00214 EMBL ACO03546.1
Ordered Locus Names:	PERMA_0321

Organism

Persephonella marina (strain DSM 14350 / EX-H1) [Complete proteome] [HAMAP]

Taxonomic identifier

123214 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Hydrogenothermaceae › Persephonella

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214
Subunit structure	Homodimer By similarity. HAMAP MF_00214
Sequence similarities	Belongs to the type-I 3-dehydroquinase family. HAMAP MF_00214

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00214
Ligand	Schiff base HAMAP MF_00214 SAAS SAAS018508
Molecular function	Lyase HAMAP MF_00214 EMBL ACO03546.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	3-dehydroquinate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	125	1	Proton acceptor By similarity HAMAP MF_00214
	Active site	150	1	Schiff-base intermediate with substrate By similarity HAMAP MF_00214

Sequences

	Sequence		Length	Mass (Da)
	C0QTU9 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 0BEB395F2910A768	FASTA	229	25,999
	10 20 30 40 50 60 MEIGKYPLIA LPLDDRDLES KLSQAKSKGI DLIELRIDMF SSTQSDYVKD ISRKVKDSGF 70 80 90 100 110 120 GIIGTVRSVE EGGLKDLKDS ERIELFEAVS DYADIIDIEL RSERLHEDLV KLCRDKEKFL 130 140 150 160 170 180 LVSYHDFEKT PSEDEIQEII DRSSFGDIIK FAFMVKDVED VGRILSVTHK NRDKKIVSIG 190 200 210 220 MGDLGKITRV AGFFFGSLIT YTYIGESVAP GQIEVKELIK ELKFYGLRS

References

[1]

"Complete and draft genome sequences of six members of the Aquificales." Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A. J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001230 Genomic DNA. Translation: ACO03546.1.
RefSeq	YP_002730114.1. NC_012440.1.
3D structure databases
ProteinModelPortal	C0QTU9.
ModBase	Search...
Protein-protein interaction databases
STRING	C0QTU9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7675949.
GenomeReviews	Gene locus PERMA_0321 in contig CP001230_GR.
KEGG	pmx:PERMA_0321.
PATRIC	22914115. VBIPerMar119911_0372.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	IAKIAVM.
ProtClustDB	CLSK2299257.
Family and domain databases
HAMAP	MF_00214. AroD. [Tree]
InterPro	IPR018508. 3-dehydroquinate_DH_AS. IPR013785. Aldolase_TIM. IPR001381. DHquinase_I. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K03785.
Pfam	PF01487. DHquinase_I. 1 hit. [Graphical view]
TIGRFAMs	TIGR01093. AroD. 1 hit.
PROSITE	PS01028. DEHYDROQUINASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C0QTU9_PERMH

Accession

Primary (citable) accession number: C0QTU9

Entry history

Integrated into UniProtKB/TrEMBL:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)