C0QTG9 (GCP_PERMH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	PERMA_0185

Organism

Persephonella marina (strain DSM 14350 / EX-H1) [Complete proteome] [HAMAP]

Taxonomic identifier

123214 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Hydrogenothermaceae › Persephonella

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_1000184975

Sequences

	Sequence		Length	Mass (Da)
	C0QTG9 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: AF77F8B68B87B58A	FASTA	344	38,107
	10 20 30 40 50 60 MKILGIETSC DDTAVSVYDS EEGLLSNVVS SQIKMHEEWG GVYPDLAARE HTKNIIPVLD 70 80 90 100 110 120 RALKEASVNI KDIDGIAVTV APGLIVSLVI GISVAKTLSW IYRKPLIPVH HIEAHIFASF 130 140 150 160 170 180 ITEKIDYPFI ALVVSGGHTE LYLIKGFEDY RYLGGTLDDA VGEAYDKVAR MLGLGYPGGP 190 200 210 220 230 240 VIDRLSKEGE DTVKLPRPLI NDRGKNRFNF SFSGLKTAVL REIQKGVYRK EDIARSFQEA 250 260 270 280 290 300 ATDVLLAKTI DAMKEFNIKN VVIAGGVSAN SRLREKFKEA EENHGIKAYF PPLYLCTDNG 310 320 330 340 AMVAFTGYKR FKESGTTVDY SFEGKARLRM DKFVEIIRKS SVSS

References

[1]

"Complete and draft genome sequences of six members of the Aquificales." Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A. J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14350 / EX-H1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001230 Genomic DNA. Translation: ACO04599.1.
RefSeq	YP_002729984.1. NC_012440.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C0QTG9.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7674954.
GenomeReviews	Gene locus PERMA_0185 in contig CP001230_GR.
KEGG	pmx:PERMA_0185.
PATRIC	22913849. VBIPerMar119911_0244.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_PERMH

Accession

Primary (citable) accession number: C0QTG9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 5, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program