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C0QT26 (C0QT26_PERMH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823 EMBL ACO03358.1
Ordered Locus Names:PERMA_0043
OrganismPersephonella marina (strain DSM 14350 / EX-H1) [Complete proteome] [HAMAP]
Taxonomic identifier123214 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Hydrogenothermaceae › Persephonella

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823 SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823 SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823 SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823 SAAS SAAS011763

Subcellular location

Cytoplasm By similarity HAMAP MF_00823 SAAS SAAS011763.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
C0QT26 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 5DD39162EB680F90

FASTA31435,302
        10         20         30         40         50         60 
MDIDKEIQIL SDKIKILRQE LKKGNRSVLK ELVESRKKFK KLAREKQKKL SAWERVQLAR 

        70         80         90        100        110        120 
HPKRPHTIDY IKNIFTDFVE LHGDRRFGDD KAIIAGFAFF EGIPVAVIGH EKGKDTKEKI 

       130        140        150        160        170        180 
ERNFGMPHPE GYRKAIRIMK LAEKFRRPVL TFIDTPGAYP GIGAEERGQS QAIAESIMVM 

       190        200        210        220        230        240 
GSLKTPIIAT VIGEGGSGGA LALGVADKVL MLENSIYSVI SPEGCAAILF KSQEKAPEAA 

       250        260        270        280        290        300 
ESLKITAKDL KELGIIDCIV PEPLGGAHLQ PEKMYRLMKR AIRSTLRMLM DKDPEKLVEE 

       310 
RQSKFYSMGK FVEK

« Hide

References

[1]"Complete and draft genome sequences of six members of the Aquificales."
Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.
J. Bacteriol. 191:1992-1993(2009) [PubMed: 19136599] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001230 Genomic DNA. Translation: ACO03358.1.
RefSeqYP_002729841.1. NC_012440.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC0QT26.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7674749.
GenomeReviewsGene locus PERMA_0043 in contig CP001230_GR.
KEGGpmx:PERMA_0043.
PATRIC22913563. VBIPerMar119911_0101.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGRDTKDN.
ProtClustDBCLSK2479666.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0QT26_PERMH
AccessionPrimary (citable) accession number: C0QT26
Entry history
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info