C0QRW3 (DCD_PERMH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	PERMA_1644

Organism

Persephonella marina (strain DSM 14350 / EX-H1) [Complete proteome] [HAMAP]

Taxonomic identifier

123214 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Aquificae › Aquificae › Aquificales › Hydrogenothermaceae › Persephonella › Persephonella marina

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP dUTP diphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000123155

Sequences

	Sequence		Length	Mass (Da)
	C0QRW3 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 249606C9F01274CC	FASTA	180	20,608
	10 20 30 40 50 60 MILNDRKIRE LIESKELLID PLDAVQIQPS SVDLRLGNDF LIYPEDIEIL DVRNPDLHNQ 70 80 90 100 110 120 LKKVVADDEG FIIQPKQFIL ATTREYIKLP DYLTAFVEGR SSLGRLGLFI ENAGWVDAGF 130 140 150 160 170 180 EGNITLEFYN ANSRPLKIYP GMRICQLVFA KMEEPAENPY RGKYQGQRGT TASRIFLDKD

References

[1]

"Complete and draft genome sequences of six members of the Aquificales." Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S., Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A., Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A. J. Bacteriol. 191:1992-1993(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 14350 / EX-H1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001230 Genomic DNA. Translation: ACO03860.1.
RefSeq	YP_002731409.1. NC_012440.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	123214.PERMA_1644.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO03860; ACO03860; PERMA_1644.
GeneID	7674187.
KEGG	pmx:PERMA_1644.
PATRIC	22916737. VBIPerMar119911_1655.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	CLSK692026.
Enzyme and pathway databases
BioCyc	PMAR123214:GIZP-1642-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. IPR008181. dUTP_pyroPase_sf. [Graphical view]
PANTHER	PTHR11241. PTHR11241. 1 hit.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_PERMH

Accession

Primary (citable) accession number: C0QRW3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 5, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program