Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongation factor Tu

Gene

tuf_1

Organism
Persephonella marina (strain DSM 14350 / EX-H1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR123214:GIZP-1179-MONOMER.
PMAR123214:GIZP-1193-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf_1Imported
Synonyms:tufUniRule annotation, tuf_2Imported
Ordered Locus Names:PERMA_1180Imported, PERMA_1194Imported
OrganismiPersephonella marina (strain DSM 14350 / EX-H1)Imported
Taxonomic identifieri123214 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesHydrogenothermaceaePersephonella
ProteomesiUP000001366: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi123214.PERMA_1194.

Structurei

3D structure databases

ProteinModelPortaliC0QQK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiDEGGRHN.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0QQK8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAREKFERKK EHVNVGTIGH VDHGKTTLTA AITYVLSKKG LAEFIGYGEI
60 70 80 90 100
DKAPEERDRG ITINITHVEY ETEKRHYAHV DCPGHADYIK NMITGAAQMD
110 120 130 140 150
GAILVVSAAD GPMPQTREHV LLARQVNVPY IVVFLNKCDM VDDEELLELV
160 170 180 190 200
ELEVRELLNK YEFPGDDVPV IRGSALGALN DEEKWVKSIE ELLDAMDNYI
210 220 230 240 250
PTPERATDKP FLMAIEDVFT ISGRGTVVTG RVERGTLKVG DEVEIVGLSD
260 270 280 290 300
EIRKTVVTGI EMFRKTLDEA VAGDNVGVLL RGIGKDEVER GQVLAAPGSI
310 320 330 340 350
TPHKKFKAQV YILSKEEGGR HTPFFLGYRP QFYIRTADIT GTVVELPEGQ
360 370 380 390
EMVMPGDNVE LTVELMEPVA IEEQMRFAIR EGGRTVGAGV VTQIIE
Length:396
Mass (Da):43,887
Last modified:May 5, 2009 - v1
Checksum:i6291E48B7E9B54CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001230 Genomic DNA. Translation: ACO03452.1.
CP001230 Genomic DNA. Translation: ACO03974.1.
RefSeqiYP_002730954.1. NC_012440.1.
YP_002730967.1. NC_012440.1.

Genome annotation databases

EnsemblBacteriaiACO03452; ACO03452; PERMA_1180.
ACO03974; ACO03974; PERMA_1194.
GeneIDi7675567.
7675637.
KEGGipmx:PERMA_1180.
pmx:PERMA_1194.
PATRICi22915819. VBIPerMar119911_1204.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001230 Genomic DNA. Translation: ACO03452.1.
CP001230 Genomic DNA. Translation: ACO03974.1.
RefSeqiYP_002730954.1. NC_012440.1.
YP_002730967.1. NC_012440.1.

3D structure databases

ProteinModelPortaliC0QQK8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi123214.PERMA_1194.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO03452; ACO03452; PERMA_1180.
ACO03974; ACO03974; PERMA_1194.
GeneIDi7675567.
7675637.
KEGGipmx:PERMA_1180.
pmx:PERMA_1194.
PATRICi22915819. VBIPerMar119911_1204.

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiDEGGRHN.
OrthoDBiEOG6R5C6X.

Enzyme and pathway databases

BioCyciPMAR123214:GIZP-1179-MONOMER.
PMAR123214:GIZP-1193-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Heidelberg J.F., Reysenbach A.-L., Nelson W.C.
    Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: EX-H1.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 14350 / EX-H1Imported and EX-H1Imported.

Entry informationi

Entry nameiC0QQK8_PERMH
AccessioniPrimary (citable) accession number: C0QQK8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: January 7, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.