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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei387 – 3871UniRule annotation
Active sitei515 – 5151UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciDAUT177437:GHLR-3158-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:HRM2_31600
OrganismiDesulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)
Taxonomic identifieri177437 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfobacterium
ProteomesiUP000000442 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 555555Glucose-6-phosphate isomerasePRO_1000206362Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi177437.HRM2_31600.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0QL01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKIDPAQT ESWKRLGRHY DGVKDLAMDD LFQQDPDRFK RLSMAFKDMV
60 70 80 90 100
VDVSKNRITD KTLALLMDLA RETGVKEAIA MMFRGDRINE TEGRSVLHVA
110 120 130 140 150
LRNLADTPVL VDGKDVMPGV RGVLEQMRLF STRVYSGQQT GYSNRTITDI
160 170 180 190 200
VNIGIGGSDL GPKMVATALA PYARKGLNVH FVSNVDGTHI VETLKGLDPA
210 220 230 240 250
TTLFIIASKT FTTQETMTNA ASARQWFLEG AGDPGHVAQH FVAISTNAAA
260 270 280 290 300
VEAFGIDRDN MFGFWDWVGG RYSLWSAIGL SVACYIGFDN FKRLLKGGFD
310 320 330 340 350
MDCHFRDTPL EQNIPVVLAM ISIWYVNFFN FPTEAVLPYD QGLEYFPAYL
360 370 380 390 400
QQACMESNGK STDRNGNLVA HATSPIVWGE PGTNGQHAFY QLLHQGTQIV
410 420 430 440 450
PCDFLVPAIS HNPLGDHHAL LVANCFAQAE ALMKGRGEQE VTREMTAKGM
460 470 480 490 500
DGEKLGRLLP HRVFHGNRPS NTIVFKQLTP EVLGAIIAMY EHKIFVQGVV
510 520 530 540 550
WNIFSFDQWG VELGKALASQ IFPELADHET VVTHDGSTNG LINVFKQMRS

KTCRS
Length:555
Mass (Da):61,596
Last modified:May 4, 2009 - v1
Checksum:i24BBFD4F3C399CCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001087 Genomic DNA. Translation: ACN16241.1.
RefSeqiWP_015905003.1. NC_012108.1.
YP_002604405.1. NC_012108.1.

Genome annotation databases

EnsemblBacteriaiACN16241; ACN16241; HRM2_31600.
KEGGidat:HRM2_31600.
PATRICi21686031. VBIDesAut25181_3267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001087 Genomic DNA. Translation: ACN16241.1.
RefSeqiWP_015905003.1. NC_012108.1.
YP_002604405.1. NC_012108.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi177437.HRM2_31600.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACN16241; ACN16241; HRM2_31600.
KEGGidat:HRM2_31600.
PATRICi21686031. VBIDesAut25181_3267.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiCETQAML.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciDAUT177437:GHLR-3158-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43914 / DSM 3382 / HRM2.

Entry informationi

Entry nameiG6PI_DESAH
AccessioniPrimary (citable) accession number: C0QL01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2009
Last sequence update: May 4, 2009
Last modified: March 31, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.