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C0QI26

- LFTR_DESAH

UniProt

C0QI26 - LFTR_DESAH

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciDAUT177437:GHLR-2667-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:HRM2_26680
OrganismiDesulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)
Taxonomic identifieri177437 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfobacterium
ProteomesiUP000000442: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229Leucyl/phenylalanyl-tRNA--protein transferasePRO_1000212566Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi177437.HRM2_26680.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiIGHAHSV.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

C0QI26-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPVFRLSDRL VFPSPHLARH DGLLCLGGDL TPERILLAYQ NGIFPWFSPG
60 70 80 90 100
DPLLWWSPDP RLVILPGQLR VSRSLQKRIN RNVYTITMDQ AFGRVINACA
110 120 130 140 150
DLRNRSGQGT WLVQEMIEAY IGLHERGYAH SVEAWNAGTL AGGLYGISLG
160 170 180 190 200
GCFFGESMFS TMADSSKTAL AALDRHLVKQ KFDLIDCQVK TDHLVSMGGV
210 220
EIPRKDFLTR IHGSLEKKTI KGPWIFTGF
Length:229
Mass (Da):25,602
Last modified:May 5, 2009 - v1
Checksum:i1DF7C06D4D46A238
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001087 Genomic DNA. Translation: ACN15762.1.
RefSeqiWP_015904525.1. NC_012108.1.
YP_002603926.1. NC_012108.1.

Genome annotation databases

EnsemblBacteriaiACN15762; ACN15762; HRM2_26680.
GeneIDi7501441.
KEGGidat:HRM2_26680.
PATRICi21685037. VBIDesAut25181_2782.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001087 Genomic DNA. Translation: ACN15762.1 .
RefSeqi WP_015904525.1. NC_012108.1.
YP_002603926.1. NC_012108.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 177437.HRM2_26680.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACN15762 ; ACN15762 ; HRM2_26680 .
GeneIDi 7501441.
KEGGi dat:HRM2_26680.
PATRICi 21685037. VBIDesAut25181_2782.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi IGHAHSV.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci DAUT177437:GHLR-2667-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43914 / DSM 3382 / HRM2.

Entry informationi

Entry nameiLFTR_DESAH
AccessioniPrimary (citable) accession number: C0QI26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 5, 2009
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3