C0Q7U9 (EX7S_SALPC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 small subunit
EC=3.1.11.6

Alternative name(s):
Exodeoxyribonuclease VII small subunit
Short name=Exonuclease VII small subunit

Gene names

Name:	xseB
Ordered Locus Names:	SPC_0436

Organism

Salmonella paratyphi C (strain RKS4594) [Complete proteome] [HAMAP]

Taxonomic identifier

476213 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella enterica subsp. enterica serovar Paratyphi C

Protein attributes

Sequence length	80 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00337
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337
Subunit structure	Heterooligomer composed of large and small subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the XseB family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Exonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 80	80	Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337		PRO_1000200259

Sequences

	Sequence		Length	Mass (Da)
	C0Q7U9 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: DA2048043B55BE24	FASTA	80	8,932
	10 20 30 40 50 60 MPKKNEAPAS FETALSELEH IVTRLESGDL PLEDALNEFE RGVQLARQGQ AKLQQAEQRV 70 80 QILLSDNEEA SPEPFIADNE

References

[1]

"Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi." Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H., Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L. PLoS ONE 4:E4510-E4510(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RKS4594.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000857 Genomic DNA. Translation: ACN44619.1.
RefSeq	YP_002636060.1. NC_012125.1.
3D structure databases
ProteinModelPortal	C0Q7U9.
SMR	C0Q7U9. Positions 7-67.
ModBase	Search...
Protein-protein interaction databases
STRING	476213.SPC_0436.
Proteomic databases
PRIDE	C0Q7U9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACN44619; ACN44619; SPC_0436.
GeneID	7552924.
KEGG	sei:SPC_0436.
PATRIC	32359679. VBISalEnt12305_0493.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1722.
HOGENOM	HOG000228798.
KO	K03602.
OMA	APLNDYK.
ProtClustDB	PRK00977.
Enzyme and pathway databases
BioCyc	SENT476213:GH8J-442-MONOMER.
Family and domain databases
Gene3D	1.10.287.1040. 1 hit.
HAMAP	MF_00337. Exonuc_7_S.
InterPro	IPR003761. Exonuc_VII_S. [Graphical view]
Pfam	PF02609. Exonuc_VII_S. 1 hit. [Graphical view]
PIRSF	PIRSF006488. Exonuc_VII_S. 1 hit.
ProDom	PD028235. Exonuc_VII_S. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF116842. SSF116842. 1 hit.
TIGRFAMs	TIGR01280. xseB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EX7S_SALPC

Accession

Primary (citable) accession number: C0Q7U9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 5, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program