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C0Q6I5 (C0Q6I5_SALPC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP-Rule MF_00209
EC=3.6.1.1 HAMAP-Rule MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP-Rule MF_00209
Gene names
Name:ppa HAMAP-Rule MF_00209 EMBL ACN48615.1
Ordered Locus Names:SPC_4565 EMBL ACN48615.1
OrganismSalmonella paratyphi C (strain RKS4594) [Complete proteome] [HAMAP] EMBL ACN48615.1
Taxonomic identifier476213 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP-Rule MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP-Rule MF_00209

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP-Rule MF_00209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding661Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding711Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding711Magnesium 2 By similarity HAMAP-Rule MF_00209
Metal binding1031Magnesium 1 By similarity HAMAP-Rule MF_00209

Sequences

Sequence LengthMass (Da)Tools
C0Q6I5 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 3C00EC5AA02B1BB2

FASTA17619,677
        10         20         30         40         50         60 
MSLLNVPAGK ELPEDIYVVI EIPANADPIK YEVDKESGAL FVDRFMSTAM FYPCNYGYIN 

        70         80         90        100        110        120 
HTLSLDGDPV DVLVPTPYPL QPGAVIRCRP VGVLKMTDES GEDAKLVAVP HTKLSKEYDH 

       130        140        150        160        170 
IKDVNDLPEL LKAQITHFFE HYKDLEKGKW VKVDGWDNAE AAKAEIVASF ERAAKK

« Hide

References

[1]"Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi."
Liu W.Q., Feng Y., Wang Y., Zou Q.H., Chen F., Guo J.T., Peng Y.H., Jin Y., Li Y.G., Hu S.N., Johnston R.N., Liu G.R., Liu S.L.
PLoS ONE 4:E4510-E4510(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: RKS4594 EMBL ACN48615.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000857 Genomic DNA. Translation: ACN48615.1.
RefSeqYP_002640056.1. NC_012125.1.

3D structure databases

ProteinModelPortalC0Q6I5.
SMRC0Q6I5. Positions 2-176.
ModBaseSearch...

Protein-protein interaction databases

STRING476213.SPC_4565.
C0Q6I5.

Proteomic databases

PRIDEC0Q6I5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACN48615; ACN48615; SPC_4565.
GeneID7557140.
KEGGsei:SPC_4565.
PATRIC32368103. VBISalEnt12305_4600.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHOG000236473.
KOK01507.
OMAGVANYKK.
ProtClustDBPRK01250.

Enzyme and pathway databases

BioCycSENT476213:GH8J-4656-MONOMER.

Family and domain databases

Gene3D3.90.80.10. 1 hit.
HAMAPMF_00209. Inorganic_PPase.
InterProIPR008162. Pyrophosphatase.
[Graphical view]
PANTHERPTHR10286. PTHR10286. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0Q6I5_SALPC
AccessionPrimary (citable) accession number: C0Q6I5
Entry history
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info