Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C0PZ54

- IF2_SALPC

UniProt

C0PZ54 - IF2_SALPC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Salmonella paratyphi C (strain RKS4594)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi400 – 4078GTPUniRule annotation
Nucleotide bindingi446 – 4505GTPUniRule annotation
Nucleotide bindingi500 – 5034GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSENT476213:GH8J-3410-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:SPC_3357
OrganismiSalmonella paratyphi C (strain RKS4594)
Taxonomic identifieri476213 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001599: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 892892Translation initiation factor IF-2PRO_1000118772Add
BLAST

Proteomic databases

PRIDEiC0PZ54.

Interactioni

Protein-protein interaction databases

STRINGi476213.SPC_3357.

Structurei

3D structure databases

ProteinModelPortaliC0PZ54.
SMRiC0PZ54. Positions 2-50.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini391 – 560170tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni400 – 4078G1By similarity
Regioni425 – 4295G2By similarity
Regioni446 – 4494G3By similarity
Regioni500 – 5034G4By similarity
Regioni536 – 5383G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
OMAiDNRTGGY.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0PZ54-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTDVTLKALA AERQVSVDRL VQQFADAGIR KSADDSVSAQ EKQTLLAHLN
60 70 80 90 100
REAVSGPDKL TLQRKTRSTL NIPGTGGKSK SVQIEVRKKR TFVKRDPQEA
110 120 130 140 150
ERLAAEEQAQ REAEEQARRE AEEQAKREAQ QKAEREAAEQ AKREAAEKAK
160 170 180 190 200
REAAEKDKVS NQQTDDMTKT AQAEKARREN EAAELKRKAE EEARRKLEEE
210 220 230 240 250
ARRVAEEARR MAEENKWTAT PEPVEDTSDY HVTTSQHARQ AEDENDREVE
260 270 280 290 300
GGRGRGRNAK AARPAKKGKH AESKADREEA RAAVRGGKGG KRKGSSLQQG
310 320 330 340 350
FQKPAQAVNR DVVIGETITV GELANKMAVK GSQVIKAMMK LGAMATINQV
360 370 380 390 400
IDQETAQLVA EEMGHKVILR RENELEEAVM SDRDTGAAAE PRAPVVTIMG
410 420 430 440 450
HVDHGKTSLL DYIRSTKVAS GEAGGITQHI GAYHVETDNG MITFLDTPGH
460 470 480 490 500
AAFTSMRARG AQATDIVVLV VAADDGVMPQ TIEAIQHAKA AGVPVVVAVN
510 520 530 540 550
KIDKPEADPD RVKNELSQYG ILPEEWGGES QFVHVSAKAG TGIDELLDAI
560 570 580 590 600
LLQAEVLELK AVRKGMASGA VIESFLDKGR GPVATVLVRE GTLHKGDIVL
610 620 630 640 650
CGFEYGRVRA MRNELGQEVL EAGPSIPVEI LGLSGVPAAG DEVTVVRDEK
660 670 680 690 700
KAREVALYRQ GKFREVKLAR QQKSKLENMF ANMTEGEVHE VNIVLKADVQ
710 720 730 740 750
GSVEAISDSL LKLSTDEVKV KIIGSGVGGI TETDATLAAA SNAILVGFNV
760 770 780 790 800
RADASARKVI ESESLDLRYY SVIYNLIDEV KAAMSGMLSP ELKQQIIGLA
810 820 830 840 850
EVRDVFKSPK FGAIAGCMVT EGTIKRHNPI RVLRDNVVIY EGELESLRRF
860 870 880 890
KDDVNEVRNG MECGIGVKNY NDVRVGDMIE VFEIIEIQRT IA
Length:892
Mass (Da):97,402
Last modified:May 5, 2009 - v1
Checksum:i0D690F8E64505885
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000857 Genomic DNA. Translation: ACN47442.1.
RefSeqiYP_002638883.1. NC_012125.1.

Genome annotation databases

EnsemblBacteriaiACN47442; ACN47442; SPC_3357.
PATRICi32365648. VBISalEnt12305_3417.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000857 Genomic DNA. Translation: ACN47442.1 .
RefSeqi YP_002638883.1. NC_012125.1.

3D structure databases

ProteinModelPortali C0PZ54.
SMRi C0PZ54. Positions 2-50.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 476213.SPC_3357.

Proteomic databases

PRIDEi C0PZ54.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACN47442 ; ACN47442 ; SPC_3357 .
PATRICi 32365648. VBISalEnt12305_3417.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
OMAi DNRTGGY.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci SENT476213:GH8J-3410-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR009061. DNA-bd_dom_put.
IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 1 hit.
SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi."
    Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H., Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.
    PLoS ONE 4:E4510-E4510(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RKS4594.

Entry informationi

Entry nameiIF2_SALPC
AccessioniPrimary (citable) accession number: C0PZ54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3