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C0PYP2

- EX7L_SALPC

UniProt

C0PYP2 - EX7L_SALPC

Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Salmonella paratyphi C (strain RKS4594)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
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    Functioni

    Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

    Catalytic activityi

    Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

    GO - Molecular functioni

    1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
    2. nucleic acid binding Source: InterPro

    Keywords - Molecular functioni

    Exonuclease, Hydrolase, Nuclease

    Enzyme and pathway databases

    BioCyciSENT476213:GH8J-1161-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
    Alternative name(s):
    Exodeoxyribonuclease VII large subunitUniRule annotation
    Short name:
    Exonuclease VII large subunitUniRule annotation
    Gene namesi
    Name:xseAUniRule annotation
    Ordered Locus Names:SPC_1143
    OrganismiSalmonella paratyphi C (strain RKS4594)
    Taxonomic identifieri476213 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001599: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. exodeoxyribonuclease VII complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 449449Exodeoxyribonuclease 7 large subunitPRO_1000200678Add
    BLAST

    Interactioni

    Subunit structurei

    Heterooligomer composed of large and small subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi476213.SPC_1143.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the XseA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1570.
    HOGENOMiHOG000229265.
    OMAiRLECVIF.
    OrthoDBiEOG64R65J.

    Family and domain databases

    HAMAPiMF_00378. Exonuc_7_L.
    InterProiIPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view]
    PfamiPF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00237. xseA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C0PYP2-1 [UniParc]FASTAAdd to Basket

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    MLSSQTSSIF TVSRLNQTVR LLLEQEMGQV WISGEISNFT QPASGHWYFT    50
    LKDDTAQVRC AMFRNSNRRV TFRPQHGQQV LVRANITLYE PRGDYQIIAE 100
    SMQPAGEGLL QQKYEQLKAK LQAEGLFDQQ HKQPLPSPAH CVGVITSKTG 150
    AALHDILHVL KRRDPSLPVI IYPTAVQGDD APGQIVRAIE LANARGECDV 200
    LIVGRGGGSL EDLWSFNDER VARAIFASRI PVVSAVGHET DVTIADFVAD 250
    LRAPTPSAAA EIVSRNQQEL LRQIQSAQQR LGMAMDYYLA NRSRRFTQIF 300
    HRLQQQHPQL RLARQQTALE RLRQRMGFAL EARIKQANQR QQRVSQRLSQ 350
    QNPQPRIHRA QSRIQQLEYR LTENIRSRLS EQRERFGNAV THLEAVSPLA 400
    TLARGYTVST TTDGKVLKKI KQVKAGDIMT TRLEDGWLES EVKSVTPGT 449
    Length:449
    Mass (Da):50,667
    Last modified:May 5, 2009 - v1
    Checksum:iF3EE08B9074B024F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000857 Genomic DNA. Translation: ACN45309.1.
    RefSeqiYP_002636750.1. NC_012125.1.

    Genome annotation databases

    EnsemblBacteriaiACN45309; ACN45309; SPC_1143.
    PATRICi32361106. VBISalEnt12305_1193.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000857 Genomic DNA. Translation: ACN45309.1 .
    RefSeqi YP_002636750.1. NC_012125.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 476213.SPC_1143.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACN45309 ; ACN45309 ; SPC_1143 .
    PATRICi 32361106. VBISalEnt12305_1193.

    Phylogenomic databases

    eggNOGi COG1570.
    HOGENOMi HOG000229265.
    OMAi RLECVIF.
    OrthoDBi EOG64R65J.

    Enzyme and pathway databases

    BioCyci SENT476213:GH8J-1161-MONOMER.

    Family and domain databases

    HAMAPi MF_00378. Exonuc_7_L.
    InterProi IPR003753. Exonuc_VII_L.
    IPR020579. Exonuc_VII_lsu_C.
    IPR025824. OB-fold_nuc-bd_dom.
    [Graphical view ]
    Pfami PF02601. Exonuc_VII_L. 1 hit.
    PF13742. tRNA_anti_2. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00237. xseA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi."
      Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H., Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.
      PLoS ONE 4:E4510-E4510(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RKS4594.

    Entry informationi

    Entry nameiEX7L_SALPC
    AccessioniPrimary (citable) accession number: C0PYP2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3