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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Salmonella paratyphi C (strain RKS4594)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciSENT476213:GH8J-798-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
Short name:
6-P-gluconolactonaseUniRule annotation
Gene namesi
Name:pglUniRule annotation
Ordered Locus Names:SPC_0781
OrganismiSalmonella paratyphi C (strain RKS4594)
Taxonomic identifieri476213 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001599 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3313316-phosphogluconolactonasePRO_1000185838Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi476213.SPC_0781.

Structurei

3D structure databases

ProteinModelPortaliC0PWX3.
SMRiC0PWX3. Positions 1-331.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
OMAiGHQPTET.
OrthoDBiEOG615VK7.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 2 hits.

Sequencei

Sequence statusi: Complete.

C0PWX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQTVYTASP ESQQIHVWSL NHEGTLTLVQ VVDVPGQVQP MVVSPDKRYL
60 70 80 90 100
YVGVRPEFRV LAYRIAPDDG VLTFAAESAL PGSPTHISTD HHGRFVFVGS
110 120 130 140 150
YNAGNVSVTR LQDGLPVELV DVVEGLDGCH SANITPDNRT LWVPALKQDR
160 170 180 190 200
ICLFTLSDDG HLVAQEPAEV NTVEGAGPRH MVFHPNRQYA YCVNELNSSV
210 220 230 240 250
DVWQLKNPHG EIECVQTLDM MPADFSDTRW AADIHITPDG RHLYACDRTA
260 270 280 290 300
SLITVFSVSE DGSVLSVEGF QPTEVQPRGF NIDNSGKYLI AAGQKSHHIA
310 320 330
VYEITGTQGL LTEKGRYAVG QGPMWVVVNA Y
Length:331
Mass (Da):36,393
Last modified:May 5, 2009 - v1
Checksum:i392016C887A77DD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000857 Genomic DNA. Translation: ACN44955.1.
RefSeqiWP_000815475.1. NC_012125.1.
YP_002636396.1. NC_012125.1.

Genome annotation databases

EnsemblBacteriaiACN44955; ACN44955; SPC_0781.
PATRICi32360392. VBISalEnt12305_0838.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000857 Genomic DNA. Translation: ACN44955.1.
RefSeqiWP_000815475.1. NC_012125.1.
YP_002636396.1. NC_012125.1.

3D structure databases

ProteinModelPortaliC0PWX3.
SMRiC0PWX3. Positions 1-331.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi476213.SPC_0781.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACN44955; ACN44955; SPC_0781.
PATRICi32360392. VBISalEnt12305_0838.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
OMAiGHQPTET.
OrthoDBiEOG615VK7.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00409.
BioCyciSENT476213:GH8J-798-MONOMER.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi."
    Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H., Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.
    PLoS ONE 4:E4510-E4510(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RKS4594.

Entry informationi

Entry namei6PGL_SALPC
AccessioniPrimary (citable) accession number: C0PWX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: May 27, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.