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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus equi subsp. zooepidemicus (strain H70)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei590 – 5901UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSEQU40041:GC8B-1331-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:SZO_12420Imported
OrganismiStreptococcus equi subsp. zooepidemicus (strain H70)Imported
Taxonomic identifieri553483 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001368 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi553483.SZO_12420.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C0MHJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVKKLESYN NQEIIAEEVA ILKEILESIT RRMIGDEAFA RIEEIIDLSE
60 70 80 90 100
KQDYVLLEQL IAGISNKDME LISRYFSILP LLINISEDVD LAYEINRQNN
110 120 130 140 150
TNQDYLGKLA LTIASVAEKE NAKELLEKVT VVPVLTAHPT QVQRKTVLEL
160 170 180 190 200
TNSIHNLLRR YRDVKAGVMN QNKWYSELYR YIDILMQTDI IREKKLKVKN
210 220 230 240 250
EITNVMQYYN SSLIQAITAL TSKYKTLAKD KGILLDNPKP INMGMWIGGD
260 270 280 290 300
RDGNPFVTAE TLRLSATVQS EVILRFYIDK LSALYQTFSL SSALTKTSPE
310 320 330 340 350
VERLASLSSD QSIYRENEPY RRAFHYIQVR LAKTLQELVG QPASDQLASR
360 370 380 390 400
MPATVGSLQS GVTSIVTNSS DQQAPAYKTA AAFKADLVMI EQSLIAAGDS
410 420 430 440 450
SLVEGDLQEV LQAVDIFGFF LASIDLRQDS SVQEACVAEL LKNAGMVENY
460 470 480 490 500
SALSEEQKCE ILLKELTEDP RTLSSAAVEK SELLEKELAI YTAARELKDK
510 520 530 540 550
LGEEVIKQHI ISHTESVSDM FELAIMLKEV GLIDQRQARV QIVPLFETIE
560 570 580 590 600
DLDNARAIMT QYLSYDIVKS WIATNAGYQE IMLGYSDSNK DGGYLASGWT
610 620 630 640 650
LYKAQNELTK IGEDNDVSIT FFHGRGGTVG RGGGPSYEAI TSQPFGSIKD
660 670 680 690 700
RIRLTEQGEI IENKYGNQDV AYYNLEMLIS ASINRMVTRM LTNPDEIDGF
710 720 730 740 750
RKIMDEIVED SKRIYRELVF DNPHFYDYFF EASPIKEVSS LNIGSRPAAR
760 770 780 790 800
KTITDISGLR AIPWVFSWSQ NRIMLPGWYA VGSAFKRFID KEEGNLAKLQ
810 820 830 840 850
HMYDKWPFFH SLLSNVDMVL SKSNMNIAFQ YAQLAESKEV CEVFHTILDE
860 870 880 890 900
WQLTKNVILA IAQHDELLEE TPSLKQSLDF RLPYFNVLNY IQIELIKRLR
910 920
HEQLDEDYEK LIHTTINGIA TGLRNSG
Length:927
Mass (Da):105,120
Last modified:May 5, 2009 - v1
Checksum:iE2D3E8B7EFDFFB8F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM204884 Genomic DNA. Translation: CAW99736.1.
RefSeqiYP_002744768.1. NC_012470.1.

Genome annotation databases

EnsemblBacteriaiCAW99736; CAW99736; SZO_12420.
GeneIDi23610756.
KEGGiseq:SZO_12420.
PATRICi19652244. VBIStrEqu35012_1318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM204884 Genomic DNA. Translation: CAW99736.1.
RefSeqiYP_002744768.1. NC_012470.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi553483.SZO_12420.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAW99736; CAW99736; SZO_12420.
GeneIDi23610756.
KEGGiseq:SZO_12420.
PATRICi19652244. VBIStrEqu35012_1318.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciSEQU40041:GC8B-1331-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: H70Imported.

Entry informationi

Entry nameiC0MHJ2_STRS7
AccessioniPrimary (citable) accession number: C0MHJ2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: April 29, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.