C0MGU8 (TAL_STRS7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	SZO_03700

Organism

Streptococcus equi subsp. zooepidemicus (strain H70) [Complete proteome] [HAMAP]

Taxonomic identifier

553483 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 214	214	Probable transaldolase HAMAP MF_00494		PRO_1000206475
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	C0MGU8 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 613AB30811CA7571	FASTA	214	23,209
	10 20 30 40 50 60 MKFFLDTANV EAIRAINELG VVDGVTTNPS IISREGRDFE TVIKEICEIV DGPISAEVTG 70 80 90 100 110 120 LTAEEMIAEA RSIAKWHDNV VVKIPMTTEG LKATNVLSQE GIKTNVTLIF TVSQGLMAMK 130 140 150 160 170 180 AGATYISPFI GRLEDIGADP YQLISDLRGI IDLYGFQAEI IAASIRTAAH VEAVAQLGAH 190 200 210 IATIPDPLFA KMTEHPLTTN GLKTFMEDWA SFKQ

References

[1]

"Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens." Holden M.T.G., Heather Z., Paillot R., Steward K.F., Webb K., Ainslie F., Jourdan T., Bason N.C., Holroyd N.E., Mungall K., Quail M.A., Sanders M., Simmonds M., Willey D., Brooks K., Aanensen D.M., Spratt B.G., Jolley K.A. , Maiden M.C.J., Kehoe M., Chanter N., Bentley S.D., Robinson C., Maskell D.J., Parkhill J., Waller A.S. PLoS Pathog. 5:E1000346-E1000346(2009) [PubMed: 19325880] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H70.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM204884 Genomic DNA. Translation: CAW98229.1.
RefSeq	YP_002743929.1. NC_012470.1.
3D structure databases
ProteinModelPortal	C0MGU8.
ModBase	Search...
Protein-protein interaction databases
STRING	C0MGU8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000064773; EBSTRP00000062000; EBSTRG00000065383.
GeneID	7693467.
GenomeReviews	Gene locus SZO_03700 in contig FM204884_GR.
KEGG	seq:SZO_03700.
PATRIC	19650356. VBIStrEqu35012_0393.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027173.
OMA	KMTEHPL.
ProtClustDB	PRK01362.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_STRS7

Accession

Primary (citable) accession number: C0MGU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 5, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program