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Protein

60 kDa chaperonin

Gene

groL

Organism
Streptococcus equi subsp. zooepidemicus (strain H70)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:SZO_01280
OrganismiStreptococcus equi subsp. zooepidemicus (strain H70)
Taxonomic identifieri553483 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001368 Componenti: Chromosome

Subcellular locationi

C0MES3:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002122091 – 54160 kDa chaperoninAdd BLAST541

Proteomic databases

PRIDEiC0MES3.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi40041.SZO_01280.

Structurei

3D structure databases

SMRiC0MES3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

C0MES3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKDIKFSAD ARESMVRGVD ILADTVKVTL GPKGRNVVLE KAFGSPLITN
60 70 80 90 100
DGVTIAKEIE LEDHFENMGA KLVSEVASKT NDIAGDGTTT ATVLTQAIVR
110 120 130 140 150
EGLKNVTAGA NPIGIRRGIE AATTTAVEAL KAVAQPVSGK EAIAQVAAVS
160 170 180 190 200
SRSEKVGDYI SEAMERVGND GVITIEESRG METELEVVEG MQFDRGYLSQ
210 220 230 240 250
YMVTDNEKMV ADLENPFILI TDKKISNIQD ILPLLEEVLK TSRPLLIIAD
260 270 280 290 300
DVDGEALPTL VLNKIRGTFN VVAVKAPGFG DRRKAMLEDI AVLTGGTVIT
310 320 330 340 350
EDLGLELKDA TMAALGQAAK VTVDKDNTVI VEGAGSSEAI ANRVNLIKSQ
360 370 380 390 400
LETTTSEFDR EKLQERLAKL AGGVAVIKVG AATETELKEM KLRIEDALNA
410 420 430 440 450
TRAAVEEGIV AGGGTALINV MDKVAALELD GDAATGRNIV LRALEEPVRQ
460 470 480 490 500
IAYNAGYEGS VIIDKLKNSA AGVGFNAATG EWVDMIATGI IDPVKVTRSA
510 520 530 540
LQNAASVAGL ILTTEAVVAT KPEPAAPAMP QGMDPGMMGG F
Length:541
Mass (Da):56,911
Last modified:May 5, 2009 - v1
Checksum:i6862F00911965525
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM204884 Genomic DNA. Translation: CAW97786.1.
RefSeqiWP_012677259.1. NC_012470.1.

Genome annotation databases

EnsemblBacteriaiCAW97786; CAW97786; SZO_01280.
GeneIDi7693933.
KEGGiseq:SZO_01280.

Similar proteinsi

Entry informationi

Entry nameiCH60_STRS7
AccessioniPrimary (citable) accession number: C0MES3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 5, 2009
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families