C0MDA1 (C0MDA1_STRS7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL CAW98747.1

Gene names

Ordered Locus Names:

SZO_06680

Organism

Streptococcus equi subsp. zooepidemicus (strain H70) [Complete proteome] [HAMAP]

Taxonomic identifier

553483 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	1063 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL CAW98747.1
Molecular function	Lyase EMBL CAW98747.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro carbon-oxygen lyase activity, acting on polysaccharides Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential EMBL CAW98747.1
	Chain	29 – 1063	1035	Potential EMBL CAW98747.1		PRO_5000453455

Sequences

	Sequence		Length	Mass (Da)
	C0MDA1 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: 71F29291F6E32C5F	FASTA	1,063	119,322
	10 20 30 40 50 60 MKQRKKLSSS VCSSIILACL FRAPTVLAEE KTAAKAISKE LQRVKKAPLK TEEASQESSP 70 80 90 100 110 120 DTQDASSVAT ESSLGEQLIL TGDNLLKNPQ FDQTSPAQEH QSTSLWSKES ANDWKDYKDA 130 140 150 160 170 180 SKSQGCPKIA VSDNKLTMTS DGNQRFRGCV HQTVAINPDK QYLLTFDIET KDKTGQAFAR 190 200 210 220 230 240 IIEEIKQGSG AAKEQRLWLS PMATGTEKKH QEKLYIPKLK VNQIKLELFY EAGHGQVVFD 250 260 270 280 290 300 NLSLREAGDK PSDDIKIASH YLEEQIVLPL NKHYLMEMAD YHYQIAAESS NIVRVENGLL 310 320 330 340 350 360 IPLAQGKTLL EVLDQEGQRV VTVPVEILAA EDPQTTSLIT KWCEVILGAE NFDRSSPAMV 370 380 390 400 410 420 ALNQKLDDSV TKNLAVLTKD QKSTYLWSDL ADLHQSSHMT ATCRRLEEMA KQVSSLASRY 430 440 450 460 470 480 YQDKELIRLI KDKLAWLTLN YYHPQKDIEG KANWWDFEIG TPRAIVNTLA FLYPYVTQEE 490 500 510 520 530 540 IKRYTKGISH FVPNPRQFRS TLVNPFKAIG GNLVDMGRIK IIEALLRHDK KALQDSIAAL 550 560 570 580 590 600 DTLFAFQPRG SKGEGFYEDG SYIDHTNVAY TGAYGNVLID GLSQLVPLIQ QSAASLDQKK 610 620 630 640 650 660 LEAMTHWIEQ AFLPLMVHGE LMDMNRGRSI SRENASSRQA ALEALRGMLR LADALPEQAK 670 680 690 700 710 720 IRVKGKIKAV LAFHNQEAIL ESLSSYYDMK LFKELLEDTA IQASPVKSYL SLFNQMDKLA 730 740 750 760 770 780 YYNAEKDFAF ALSLHSNKTL NFEAMNNENT RGWYTGDGMF YLYNSDLGHY SDRFWPTVNP 790 800 810 820 830 840 LKMAGTTEAE VHREDVTVAY LKKLTNDYKE KAKEKAGMST QQSSFVGAIK AGDKTALAVM 850 860 870 880 890 900 DFQNWDRTVS AKKSWTILDD QIVFLGTAIT SQTHQAVTTT IDQRKENPDN SYILFINGQE 910 920 930 940 950 960 TALTEEVLHR DDVTSLLLLS KDGQANIGYL FAKPTALALS RKVQSGCWSE INTNSNNKDL 970 980 990 1000 1010 1020 ISQSFITISQ THSQASDSYA YTLLPNISKA DFDKVCSEAR IEVLRNDSKL QLIHDKKQGL 1030 1040 1050 1060 LAVVKYNQAK EVVNGQLSLE KSGLYLYQKV GNDFKQLSFK ALS

References

[1]

"Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens." Holden M.T.G., Heather Z., Paillot R., Steward K.F., Webb K., Ainslie F., Jourdan T., Bason N.C., Holroyd N.E., Mungall K., Quail M.A., Sanders M., Simmonds M., Willey D., Brooks K., Aanensen D.M., Spratt B.G., Jolley K.A. , Maiden M.C.J., Kehoe M., Chanter N., Bentley S.D., Robinson C., Maskell D.J., Parkhill J., Waller A.S. PLoS Pathog. 5:E1000346-E1000346(2009) [PubMed: 19325880] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM204884 Genomic DNA. Translation: CAW98747.1.
RefSeq	YP_002744212.1. NC_012470.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C0MDA1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000066042; EBSTRP00000061084; EBSTRG00000065234.
GeneID	7693321.
GenomeReviews	Gene locus SZO_06680 in contig FM204884_GR.
KEGG	seq:SZO_06680.
PATRIC	19651011. VBIStrEqu35012_0707.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000027679.
OMA	GSYIDHT.
ProtClustDB	CLSK2803397.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR008979. Galactose-bd-like. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR023295. Hyaluronate_lyase_beta_dom. IPR014756. Ig_E-set. IPR011071. Lyase_8-like_C. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.40.1380. Hyaluronate_lyase_beta_dom. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF49785. Gal_bind_like. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF81296. Ig_E-set. 1 hit. SSF49863. Lyase_like_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C0MDA1_STRS7

Accession

Primary (citable) accession number: C0MDA1

Entry history

Integrated into UniProtKB/TrEMBL:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)