C0MCG2 (C0MCG2_STRS7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycosyl hydrolase family protein EMBL CAW98510.1

Gene names

Ordered Locus Names:

SZO_05310 EMBL CAW98510.1

Organism

Streptococcus equi subsp. zooepidemicus (strain H70) [Complete proteome] [HAMAP]

Taxonomic identifier

553483 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus dysgalactiae group › Streptococcus equi › Streptococcus equi subsp. zooepidemicus

Protein attributes

Sequence length	1546 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS005877
Domain	Signal EMBL CAW98510.1
Molecular function	Hydrolase EMBL CAW98510.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups other than amino-acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 42	42	Potential EMBL CAW98510.1
	Chain	43 – 1546	1504	Potential EMBL CAW98510.1		PRO_5000453409

Sequences

	Sequence		Length	Mass (Da)
	C0MCG2 [UniParc]. Last modified May 5, 2009. Version 1. Checksum: EC1A64DB75AB7E72	FASTA	1,546	169,787
	10 20 30 40 50 60 MLFNPIGKEQ IRKYAIKKLS VGVASVCVGI GLAAGLPVVV YADDVSEVSL QQPTKAAVTE 70 80 90 100 110 120 ISHEQEPQAT DTDSEALVVS EETTVDEAVV ANAVTSNAAD QTADEEKSNA PVELNKVANG 130 140 150 160 170 180 GFDNDYVSNK NQWQYREGGH SVLTTENNNS YAEVTSGTLD EHILQKVSTT VGKTYTLEAD 190 200 210 220 230 240 VKVEADTPHN GLYLTAKESN HNLQGPVIKE VSLTDTDGTW SHIKLSFTAT TSETFVGLVK 250 260 270 280 290 300 RLEASSPETL AASASIDNVS VVEENDYELI WQDEFSGDQL NQENWGYELG SIRGNEQQHY 310 320 330 340 350 360 TDSTENIYLE NGNLVLNVTE RKGEDRYANP RGGTSARQVI YDSGSVRTVG KQEFLYGRIE 370 380 390 400 410 420 ARAKLPKGKG AFPAFWTLGA DFTLDGDIAS TQGYGWPSTG ELDIMELIGA PNGEHEGELA 430 440 450 460 470 480 EGDQSNKTVY GTPHFYYVKG DADKDGSYSP TALGGNLTLS DDFYDDYHIF GINWYPDKIE 490 500 510 520 530 540 WYVDGIVYNT MYLTGDERLE AAAAAFNKPQ YLQFNLATGG NWSKNAGYYL ASDETAFVID 550 560 570 580 590 600 YVRYYQDAEQ KAASEAYYAS QPDLKGVKDL TMLEGTSPDL AQAVTTDQEG YVVDFSVENE 610 620 630 640 650 660 YLFTNKGGNT NAALQAAGRD DLSALSELAP GIYNIYYSAV PYNADLGSTV TPTAKIAREV 670 680 690 700 710 720 AILTVLPKEG LIGKKGEPLS TVALPANWQW VTPEEILGSA EHYQIKYTTE GGRAIYTSIE 730 740 750 760 770 780 ASYISDQPIS DQASILVDLG NAILDATAEK AAVTDDEALS KLDDVMSLNQ GTVTIRYRLD 790 800 810 820 830 840 TADTTVRSSS PLALLSISNQ ASANEYASFF IEPKNNKIGL EFKGAEVPIV KVGSGFNLLT 850 860 870 880 890 900 NSDWQTISYV FTGSRLKIYL NGDLYGEADF AGFMKQLPWK ASADTLTIGG LKRTYDGESV 910 920 930 940 950 960 LHWGLKGLVD QVLIDTDVYD LTDIAKAHQS TLRPVTGEKT NVWDKYDEGV FEYRIPSVVK 970 980 990 1000 1010 1020 TPSGTLIAAA DARKKHYNDW GDVATVVRIS HDDGKTWSNN ITVLDMPTQP YFTTQYSLAD 1030 1040 1050 1060 1070 1080 WNTNMTQSAF SIDSTLLTDA SGKLYLLVDV FPESQGAVAS KAGSGYELIN GQYYLNLYDF 1090 1100 1110 1120 1130 1140 DNNKYTVREG GIVYDQNGHQ TDMYVDEGNF ETAFSTRGNL YQTEAGEDIL LGNIYLRSGR 1150 1160 1170 1180 1190 1200 TKQGITREGS QTAPLFTYMT SFLWLLTSED EGQTWSTPLD ITPQIKEDWM GFLGTGAAAG 1210 1220 1230 1240 1250 1260 IEIDAVNAEG EQVKRLVFPI YYTNQQNATS ASLGRQSSAN IFSDDGGQTW QRGESPNDGR 1270 1280 1290 1300 1310 1320 IYGHNQQTTS KDFDTSVTEL TENQIIQLNN GHLLQFMRNT GKTIVIARST DYGATWEDNP 1330 1340 1350 1360 1370 1380 TVTDLPEPYV NLSAIHMMVD GKEYVVLSNP LGEPSGEQLT IRNQRMKGIL RVGEVLEDDS 1390 1400 1410 1420 1430 1440 INWVASTIFE PKRFAYSSLV QLDDERVGLL YEYSGQITYS TFNIKQMISD QFREDKAEIE 1450 1460 1470 1480 1490 1500 EVTITSAAPK QNGKASITIQ MTFNQPMFIL GDRQLAVTVN GVDKLASYVS GDGTDTAIFE 1510 1520 1530 1540 LSLESMPEGP ITVLPQFDHT IVETKYGIRL TDDKAYTVSY PAAVTA

References

[1]

"Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens." Holden M.T.G., Heather Z., Paillot R., Steward K.F., Webb K., Ainslie F., Jourdan T., Bason N.C., Holroyd N.E., Mungall K., Quail M.A., Sanders M., Simmonds M., Willey D., Brooks K., Aanensen D.M., Spratt B.G., Jolley K.A. , Maiden M.C.J., Kehoe M., Chanter N., Bentley S.D., Robinson C., Maskell D.J., Parkhill J., Waller A.S. PLoS Pathog. 5:e1000346-e1000346(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H70 EMBL CAW98510.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM204884 Genomic DNA. Translation: CAW98510.1.
RefSeq	YP_002744087.1. NC_012470.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	553483.SZO_05310.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAW98510; CAW98510; SZO_05310.
GeneID	7695084.
KEGG	seq:SZO_05310.
PATRIC	19650718. VBIStrEqu35012_0562.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2273.
HOGENOM	HOG000071801.
KO	K01186.
OMA	TEISHEQ.
ProtClustDB	CLSK2480273.
Enzyme and pathway databases
BioCyc	SEQU40041:GC8B-608-MONOMER.
Family and domain databases
Gene3D	2.120.10.10. 2 hits. 2.60.120.200. 1 hit. 2.60.120.260. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR008979. Galactose-bd-like. IPR000757. Glyco_hydro_16. IPR004124. Glyco_hydro_33_N. IPR005877. Gpos_YSIRK. IPR011040. Sialidases. IPR020610. Thiolase_AS. [Graphical view]
Pfam	PF00722. Glyco_hydro_16. 1 hit. PF02973. Sialidase. 1 hit. PF04650. YSIRK_signal. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 2 hits. SSF49785. Gal_bind_like. 1 hit. SSF50939. Sialidase. 1 hit.
TIGRFAMs	TIGR01168. YSIRK_signal. 1 hit.
PROSITE	PS00099. THIOLASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C0MCG2_STRS7

Accession

Primary (citable) accession number: C0MCG2

Entry history

Integrated into UniProtKB/TrEMBL:	May 5, 2009
Last sequence update:	May 5, 2009
Last modified:	May 29, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)