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C0M712 (GLGA_STRE4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:SEQ_0913
OrganismStreptococcus equi subsp. equi (strain 4047) [Complete proteome] [HAMAP]
Taxonomic identifier553482 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Glycogen synthase HAMAP-Rule MF_00484
PRO_1000190083

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
C0M712 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: B3191E133E27F6AE

FASTA47653,670
        10         20         30         40         50         60 
MKIMFVAAEG APFAKTGGLG DVIGALPKSL VKNGHEVSVI LPYYDVVDQA FGQQVEDVLY 

        70         80         90        100        110        120 
FYTQVGWRRQ YVGIKKLVKD KVTFYFIDNQ GYFFRGRIYG DWDDGERFAY FQLAAIEAME 

       130        140        150        160        170        180 
KIGVIPDILH VHDYHTAMIP FLLKEKYHWI QAYQAIRTVF TIHNIAFQGQ FDPGMLGDLF 

       190        200        210        220        230        240 
DVGIERYEDG TLRWHDCLNW MKAAVLYADR VTTVSPSYAH EIQTPAFGQG LDQVMRMEAG 

       250        260        270        280        290        300 
KLSGIVNGID TDLFNPARDP HLPASFSAED LSGKAATKQA LQERLGLPVR ADVPLIGMVS 

       310        320        330        340        350        360 
RLTDQKGFQL VLEELPHILQ QDVQLVLLGT GDPDYEAAFS WFAKAYPEKL SANITFDLPL 

       370        380        390        400        410        420 
AQQIYGACDL FLMPSAFEPC GLSQMMAMRY GAIPIVHEIG GLKDTVASYN AYEKTGTGFG 

       430        440        450        460        470 
FDQFSGFWLT QTLLFALDIY HNHKEDWQTI QQHAMTKDFS WDTASLAYLD LYKSLL 

« Hide

References

[1]"Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens."
Holden M.T.G., Heather Z., Paillot R., Steward K.F., Webb K., Ainslie F., Jourdan T., Bason N.C., Holroyd N.E., Mungall K., Quail M.A., Sanders M., Simmonds M., Willey D., Brooks K., Aanensen D.M., Spratt B.G., Jolley K.A. expand/collapse author list , Maiden M.C.J., Kehoe M., Chanter N., Bentley S.D., Robinson C., Maskell D.J., Parkhill J., Waller A.S.
PLoS Pathog. 5:E1000346-E1000346(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 4047.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM204883 Genomic DNA. Translation: CAW93423.1.
RefSeqYP_002746242.1. NC_012471.1.

3D structure databases

ProteinModelPortalC0M712.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING553482.SEQ_0913.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAW93423; CAW93423; SEQ_0913.
GeneID7695878.
KEGGseu:SEQ_0913.
PATRIC19646616. VBIStrEqu13040_0929.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAPYHDESQ.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycSEQU553482:GJOY-919-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_STRE4
AccessionPrimary (citable) accession number: C0M712
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: May 14, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways