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Protein
Submitted name:

Estrogen receptor alpha delta 6,7 isoform

Gene

ESR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Estrogen receptor alpha delta 6,7 isoformImported
Gene namesi
Name:ESR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PeptideAtlasiC0LLI8

Structurei

3D structure databases

SMRiC0LLI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 220NR LBDInterPro annotationAdd BLAST143

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
SUPFAMiSSF48508 SSF48508, 2 hits
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit

Sequencei

Sequence statusi: Fragment.

C0LLI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RKSCQACRLR KCYEVGMMKG GIRKDRRGGR MLKHKRQRDD GEGRGEVGSA
60 70 80 90 100
GDMRAANLWP SPLMIKRSKK NSLALSLTAD QMVSALLDAE PPILYSEYDP
110 120 130 140 150
TRPFSEASMM GLLTNLADRE LVHMINWAKR VPGFVDLTLH DQVHLLECAW
160 170 180 190 200
LEILMIGLVW RSMEHPGKLL FAPNLLLDSN KGMEHLYSMK CKNVVPLYDL
210 220
LLEMLDAHRL HAPTSRGGAS
Length:220
Mass (Da):24,824
Last modified:May 5, 2009 - v1
Checksum:i46E64AD1B165FD7C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei220Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ716814 mRNA Translation: ACN89825.1
UniGeneiHs.208124
Hs.744830

Similar proteinsi

Entry informationi

Entry nameiC0LLI8_HUMAN
AccessioniPrimary (citable) accession number: C0LLI8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 5, 2009
Last sequence update: May 5, 2009
Last modified: May 23, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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