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C0LLI8

- C0LLI8_HUMAN

UniProt

C0LLI8 - C0LLI8_HUMAN

Protein
Submitted name:

Estrogen receptor alpha delta 6,7 isoform

Gene

ESR1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro
    3. steroid hormone receptor activity Source: InterPro
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    ReceptorImported

    Keywords - Biological processi

    Transcription, Transcription regulationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Estrogen receptor alpha delta 6,7 isoformImported
    Gene namesi
    Name:ESR1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW

    Keywords - Cellular componenti

    NucleusSAAS annotation

    Family & Domainsi

    Family and domain databases

    Gene3Di1.10.565.10. 3 hits.
    InterProiIPR008946. Nucl_hormone_rcpt_ligand-bd.
    IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
    IPR001723. Str_hrmn_rcpt.
    IPR001628. Znf_hrmn_rcpt.
    [Graphical view]
    PfamiPF00104. Hormone_recep. 1 hit.
    PF00105. zf-C4. 1 hit.
    [Graphical view]
    PRINTSiPR00398. STRDHORMONER.
    SMARTiSM00430. HOLI. 1 hit.
    [Graphical view]
    SUPFAMiSSF48508. SSF48508. 2 hits.

    Sequencei

    Sequence statusi: Fragment.

    C0LLI8-1 [UniParc]FASTAAdd to Basket

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    RKSCQACRLR KCYEVGMMKG GIRKDRRGGR MLKHKRQRDD GEGRGEVGSA    50
    GDMRAANLWP SPLMIKRSKK NSLALSLTAD QMVSALLDAE PPILYSEYDP 100
    TRPFSEASMM GLLTNLADRE LVHMINWAKR VPGFVDLTLH DQVHLLECAW 150
    LEILMIGLVW RSMEHPGKLL FAPNLLLDSN KGMEHLYSMK CKNVVPLYDL 200
    LLEMLDAHRL HAPTSRGGAS 220
    Length:220
    Mass (Da):24,824
    Last modified:May 5, 2009 - v1
    Checksum:i46E64AD1B165FD7C
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei220 – 2201Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ716814 mRNA. Translation: ACN89825.1.
    UniGeneiHs.208124.
    Hs.744830.

    Genome annotation databases

    UCSCiuc011eex.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ716814 mRNA. Translation: ACN89825.1 .
    UniGenei Hs.208124.
    Hs.744830.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc011eex.2. human.

    Miscellaneous databases

    ChiTaRSi ESR1. human.
    NextBioi 35482431.

    Family and domain databases

    Gene3Di 1.10.565.10. 3 hits.
    InterProi IPR008946. Nucl_hormone_rcpt_ligand-bd.
    IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
    IPR001723. Str_hrmn_rcpt.
    IPR001628. Znf_hrmn_rcpt.
    [Graphical view ]
    Pfami PF00104. Hormone_recep. 1 hit.
    PF00105. zf-C4. 1 hit.
    [Graphical view ]
    PRINTSi PR00398. STRDHORMONER.
    SMARTi SM00430. HOLI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48508. SSF48508. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Decreased alternative splicing of estrogen receptor-alpha mRNA in the Alzheimer's disease brain."
      Ishunina T.A., Swaab D.F.
      Neurobiol. Aging 33:286-296(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Substantia nigraImported.

    Entry informationi

    Entry nameiC0LLI8_HUMAN
    AccessioniPrimary (citable) accession number: C0LLI8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 5, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.