Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C0LGU0

- RLK_ARATH

UniProt

C0LGU0 - RLK_ARATH

Protein

Probable LRR receptor-like serine/threonine-protein kinase RLK

Gene

RLK

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (05 May 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei385 – 3851ATPPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi363 – 3719ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G35390-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable LRR receptor-like serine/threonine-protein kinase RLK (EC:2.7.11.1)
    Gene namesi
    Name:RLK
    Ordered Locus Names:At5g35390
    ORF Names:T26D22.9
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G35390.

    Subcellular locationi

    Cell membrane 1 Publication; Single-pass type I membrane protein 1 Publication
    Note: Preferentially localized to the apical region of the pollen tube plasma membrane.

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3131Sequence AnalysisAdd
    BLAST
    Chaini32 – 662631Probable LRR receptor-like serine/threonine-protein kinase RLKPRO_0000387521Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi197 – 1971N-linked (GlcNAc...)Sequence Analysis
    Modified residuei359 – 3591PhosphoserineBy similarity
    Modified residuei437 – 4371PhosphoserineBy similarity
    Modified residuei457 – 4571PhosphothreonineBy similarity
    Modified residuei527 – 5271PhosphotyrosineBy similarity

    Keywords - PTMi

    Glycoprotein, Phosphoprotein

    Proteomic databases

    PaxDbiC0LGU0.
    PRIDEiC0LGU0.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT5G35390.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliC0LGU0.
    SMRiC0LGU0. Positions 46-242, 322-638.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini32 – 256225ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini278 – 662385CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei257 – 27721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati79 – 9820LRR 1Add
    BLAST
    Repeati99 – 12123LRR 2Add
    BLAST
    Repeati122 – 14423LRR 3Add
    BLAST
    Repeati147 – 16923LRR 4Add
    BLAST
    Repeati171 – 19121LRR 5Add
    BLAST
    Repeati192 – 21423LRR 6Add
    BLAST
    Domaini357 – 639283Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 6 LRR (leucine-rich) repeats.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiKOG0619.
    HOGENOMiHOG000116554.
    InParanoidiO65240.
    OMAiRTLSFMD.
    PhylomeDBiC0LGU0.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR001611. Leu-rich_rpt.
    IPR013210. LRR-contain_N2.
    IPR000719. Prot_kinase_dom.
    [Graphical view]
    PfamiPF00560. LRR_1. 1 hit.
    PF13855. LRR_8. 1 hit.
    PF08263. LRRNT_2. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    C0LGU0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPMQARTLS VYNVMVPLVC LLLFFSTPTH GLSDSEAILK FKESLVVGQE    50
    NALASWNAKS PPCTWSGVLC NGGSVWRLQM ENLELSGSID IEALSGLTSL 100
    RTLSFMNNKF EGPFPDFKKL AALKSLYLSN NQFGGDIPGD AFEGMGWLKK 150
    VHLAQNKFTG QIPSSVAKLP KLLELRLDGN QFTGEIPEFE HQLHLLNLSN 200
    NALTGPIPES LSMTDPKVFE GNKGLYGKPL ETECDSPYIE HPPQSEARPK 250
    SSSRGPLVIT AIVAALTILI ILGVIFLLNR SYKNKKPRLA VETGPSSLQK 300
    KTGIREADQS RRDRKKADHR KGSGTTKRMG AAAGVENTKL SFLREDREKF 350
    DLQDLLKASA EILGSGCFGA SYKAVLSSGQ MMVVKRFKQM NNAGRDEFQE 400
    HMKRLGRLMH HNLLSIVAYY YRKEEKLLVC DFAERGSLAI NLHSNQSLGK 450
    PSLDWPTRLK IVKGVAKGLF YLHQDLPSLM APHGHLKSSN VLLTKTFEPL 500
    LTDYGLIPLI NQEKAQMHMA AYRSPEYLQH RRITKKTDVW GLGILILEIL 550
    TGKFPANFSQ SSEEDLASWV NSGFHGVWAP SLFDKGMGKT SHCEGQILKL 600
    LTIGLNCCEP DVEKRLDIGQ AVEKIEELKE REGDDDDFYS TYVSETDGRS 650
    SKGESCESIS FA 662
    Length:662
    Mass (Da):73,483
    Last modified:May 5, 2009 - v1
    Checksum:i1F441F0B84D9CE8C
    GO

    Sequence cautioni

    The sequence AAC13607.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence BAB11489.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF058826 Genomic DNA. Translation: AAC13607.1. Sequence problems.
    AB025636 Genomic DNA. Translation: BAB11489.1. Sequence problems.
    CP002688 Genomic DNA. Translation: AED93962.1.
    FJ708784 mRNA. Translation: ACN59375.1.
    PIRiT01183.
    RefSeqiNP_198389.2. NM_122930.2.
    UniGeneiAt.55132.

    Genome annotation databases

    EnsemblPlantsiAT5G35390.1; AT5G35390.1; AT5G35390.
    GeneIDi833500.
    KEGGiath:AT5G35390.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF058826 Genomic DNA. Translation: AAC13607.1 . Sequence problems.
    AB025636 Genomic DNA. Translation: BAB11489.1 . Sequence problems.
    CP002688 Genomic DNA. Translation: AED93962.1 .
    FJ708784 mRNA. Translation: ACN59375.1 .
    PIRi T01183.
    RefSeqi NP_198389.2. NM_122930.2.
    UniGenei At.55132.

    3D structure databases

    ProteinModelPortali C0LGU0.
    SMRi C0LGU0. Positions 46-242, 322-638.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT5G35390.1-P.

    Proteomic databases

    PaxDbi C0LGU0.
    PRIDEi C0LGU0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G35390.1 ; AT5G35390.1 ; AT5G35390 .
    GeneIDi 833500.
    KEGGi ath:AT5G35390.

    Organism-specific databases

    GeneFarmi 550. 47.
    TAIRi AT5G35390.

    Phylogenomic databases

    eggNOGi KOG0619.
    HOGENOMi HOG000116554.
    InParanoidi O65240.
    OMAi RTLSFMD.
    PhylomeDBi C0LGU0.

    Enzyme and pathway databases

    BioCyci ARA:AT5G35390-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR001611. Leu-rich_rpt.
    IPR013210. LRR-contain_N2.
    IPR000719. Prot_kinase_dom.
    [Graphical view ]
    Pfami PF00560. LRR_1. 1 hit.
    PF13855. LRR_8. 1 hit.
    PF08263. LRRNT_2. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
      Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
      , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
      Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. "Structural analysis of Arabidopsis thaliana chromosome 5. XI."
      Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
      Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
      Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
      BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth."
      Lee Y.J., Szumlanski A., Nielsen E., Yang Z.
      J. Cell Biol. 181:1155-1168(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiRLK_ARATH
    AccessioniPrimary (citable) accession number: C0LGU0
    Secondary accession number(s): O65240
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 3, 2009
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3