Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C0LGU0 (RLK_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase RLK

EC=2.7.11.1
Gene names
Name:RLK
Ordered Locus Names:At5g35390
ORF Names:T26D22.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length662 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein. Note: Preferentially localized to the apical region of the pollen tube plasma membrane. Ref.5

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 6 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAC13607.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence BAB11489.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential
Chain32 – 662631Probable LRR receptor-like serine/threonine-protein kinase RLK
PRO_0000387521

Regions

Topological domain32 – 256225Extracellular Potential
Transmembrane257 – 27721Helical; Potential
Topological domain278 – 662385Cytoplasmic Potential
Repeat79 – 9820LRR 1
Repeat99 – 12123LRR 2
Repeat122 – 14423LRR 3
Repeat147 – 16923LRR 4
Repeat171 – 19121LRR 5
Repeat192 – 21423LRR 6
Domain357 – 639283Protein kinase
Nucleotide binding363 – 3719ATP By similarity

Sites

Binding site3851ATP By similarity

Amino acid modifications

Modified residue3591Phosphoserine By similarity
Modified residue4371Phosphoserine By similarity
Modified residue4571Phosphothreonine By similarity
Modified residue5271Phosphotyrosine By similarity
Glycosylation1971N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
C0LGU0 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 1F441F0B84D9CE8C

FASTA66273,483
        10         20         30         40         50         60 
MPPMQARTLS VYNVMVPLVC LLLFFSTPTH GLSDSEAILK FKESLVVGQE NALASWNAKS 

        70         80         90        100        110        120 
PPCTWSGVLC NGGSVWRLQM ENLELSGSID IEALSGLTSL RTLSFMNNKF EGPFPDFKKL 

       130        140        150        160        170        180 
AALKSLYLSN NQFGGDIPGD AFEGMGWLKK VHLAQNKFTG QIPSSVAKLP KLLELRLDGN 

       190        200        210        220        230        240 
QFTGEIPEFE HQLHLLNLSN NALTGPIPES LSMTDPKVFE GNKGLYGKPL ETECDSPYIE 

       250        260        270        280        290        300 
HPPQSEARPK SSSRGPLVIT AIVAALTILI ILGVIFLLNR SYKNKKPRLA VETGPSSLQK 

       310        320        330        340        350        360 
KTGIREADQS RRDRKKADHR KGSGTTKRMG AAAGVENTKL SFLREDREKF DLQDLLKASA 

       370        380        390        400        410        420 
EILGSGCFGA SYKAVLSSGQ MMVVKRFKQM NNAGRDEFQE HMKRLGRLMH HNLLSIVAYY 

       430        440        450        460        470        480 
YRKEEKLLVC DFAERGSLAI NLHSNQSLGK PSLDWPTRLK IVKGVAKGLF YLHQDLPSLM 

       490        500        510        520        530        540 
APHGHLKSSN VLLTKTFEPL LTDYGLIPLI NQEKAQMHMA AYRSPEYLQH RRITKKTDVW 

       550        560        570        580        590        600 
GLGILILEIL TGKFPANFSQ SSEEDLASWV NSGFHGVWAP SLFDKGMGKT SHCEGQILKL 

       610        620        630        640        650        660 
LTIGLNCCEP DVEKRLDIGQ AVEKIEELKE REGDDDDFYS TYVSETDGRS SKGESCESIS 


FA 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]"Structural analysis of Arabidopsis thaliana chromosome 5. XI."
Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H., Tabata S.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Rho-GTPase-dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth."
Lee Y.J., Szumlanski A., Nielsen E., Yang Z.
J. Cell Biol. 181:1155-1168(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF058826 Genomic DNA. Translation: AAC13607.1. Sequence problems.
AB025636 Genomic DNA. Translation: BAB11489.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED93962.1.
FJ708784 mRNA. Translation: ACN59375.1.
PIRT01183.
RefSeqNP_198389.2. NM_122930.2.
UniGeneAt.55132.

3D structure databases

ProteinModelPortalC0LGU0.
SMRC0LGU0. Positions 46-242, 322-638.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G35390.1-P.

Proteomic databases

PaxDbC0LGU0.
PRIDEC0LGU0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G35390.1; AT5G35390.1; AT5G35390.
GeneID833500.
KEGGath:AT5G35390.

Organism-specific databases

GeneFarm550. 47.
TAIRAT5G35390.

Phylogenomic databases

eggNOGKOG0619.
HOGENOMHOG000116554.
InParanoidO65240.
OMARTLSFMD.
PhylomeDBC0LGU0.

Enzyme and pathway databases

BioCycARA:AT5G35390-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamPF00560. LRR_1. 1 hit.
PF13855. LRR_8. 1 hit.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLK_ARATH
AccessionPrimary (citable) accession number: C0LGU0
Secondary accession number(s): O65240
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: June 11, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names