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Protein

Probable LRR receptor-like serine/threonine-protein kinase At4g31250

Gene

At4g31250

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei394ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi372 – 380ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable LRR receptor-like serine/threonine-protein kinase At4g31250 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:At4g31250
ORF Names:F8F16.70
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G31250
TAIRilocus:2128156 AT4G31250

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini27 – 242ExtracellularSequence analysisAdd BLAST216
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Topological domaini264 – 676CytoplasmicSequence analysisAdd BLAST413

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000038755627 – 676Probable LRR receptor-like serine/threonine-protein kinase At4g31250Add BLAST650

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi42N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi73N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi218N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei368PhosphoserineBy similarity1
Modified residuei446PhosphoserineBy similarity1
Modified residuei543PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiC0LGR9
PRIDEiC0LGR9

PTM databases

iPTMnetiC0LGR9

Expressioni

Gene expression databases

ExpressionAtlasiC0LGR9 baseline and differential
GenevisibleiC0LGR9 AT

Interactioni

Protein-protein interaction databases

BioGridi14538, 18 interactors
STRINGi3702.AT4G31250.1

Structurei

3D structure databases

ProteinModelPortaliC0LGR9
SMRiC0LGR9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati98 – 122LRR 1Add BLAST25
Repeati123 – 146LRR 2Add BLAST24
Repeati148 – 171LRR 3Add BLAST24
Repeati172 – 195LRR 4Add BLAST24
Repeati197 – 218LRR 5Add BLAST22
Domaini366 – 640Protein kinasePROSITE-ProRule annotationAdd BLAST275

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IHM4 Eukaryota
COG0515 LUCA
HOGENOMiHOG000116554
InParanoidiC0LGR9
OMAiGKASQWF
OrthoDBiEOG093605TP
PhylomeDBiC0LGR9

Family and domain databases

Gene3Di3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR032675 LRR_dom_sf
IPR013210 LRR_N_plant-typ
IPR000719 Prot_kinase_dom
PfamiView protein in Pfam
PF08263 LRRNT_2, 1 hit
PF00069 Pkinase, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: C0LGR9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTRDDKFPIV YSLLLIVLLF VSPIYGDGDA DALLKFKSSL VNASSLGGWD
60 70 80 90 100
SGEPPCSGDK GSDSKWKGVM CSNGSVFALR LENMSLSGEL DVQALGSIRG
110 120 130 140 150
LKSISFMRNH FEGKIPRGID GLVSLAHLYL AHNQFTGEID GDLFSGMKAL
160 170 180 190 200
LKVHLEGNRF SGEIPESLGK LPKLTELNLE DNMFTGKIPA FKQKNLVTVN
210 220 230 240 250
VANNQLEGRI PLTLGLMNIT FFSGNKGLCG APLLPCRYTR PPFFTVFLLA
260 270 280 290 300
LTILAVVVLI TVFLSVCILS RRQGKGQDQI QNHGVGHFHG QVYGQPEQQQ
310 320 330 340 350
HSEKSSQDSK VYRKLANETV QRDSTATSGA ISVGGLSPDE DKRGDQRKLH
360 370 380 390 400
FVRNDQERFT LQDMLRASAE VLGSGGFGSS YKAALSSGRA VVVKRFRFMS
410 420 430 440 450
NIGREEFYDH MKKIGRLSHP NLLPLIAFYY RKEEKLLVTN YISNGSLANL
460 470 480 490 500
LHANRTPGQV VLDWPIRLKI VRGVTRGLAY LYRVFPDLNL PHGHLKSSNV
510 520 530 540 550
LLDPNFEPLL TDYALVPVVN RDQSQQFMVA YKAPEFTQQD RTSRRSDVWS
560 570 580 590 600
LGILILEILT GKFPANYLRQ GKGADDELAA WVESVARTEW TADVFDKEMK
610 620 630 640 650
AGKEHEAQML KLLKIGLRCC DWDIEKRIEL HEAVDRIEEV DRDAGGGQES
660 670
VRSSYVTASD GDHRSSRAMT EEFSLM
Length:676
Mass (Da):75,235
Last modified:May 5, 2009 - v1
Checksum:i65162EF1D0782579
GO
Isoform 2 (identifier: C0LGR9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-88: Missing.
     89-98: ELDVQALGSI → MERSDVFKRL

Note: No experimental confirmation available.
Show »
Length:588
Mass (Da):66,126
Checksum:iA2CA3D49FE525576
GO

Sequence cautioni

The sequence CAA16528 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79843 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti487 – 488DL → RI in BAF00232 (Ref. 3) Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0382931 – 88Missing in isoform 2. 1 PublicationAdd BLAST88
Alternative sequenceiVSP_03829489 – 98ELDVQALGSI → MERSDVFKRL in isoform 2. 1 Publication10

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021633 Genomic DNA Translation: CAA16528.1 Sequence problems.
AL161578 Genomic DNA Translation: CAB79843.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE85882.1
AK176198 mRNA Translation: BAD43961.1
AK176233 mRNA Translation: BAD43996.1
AK176245 mRNA Translation: BAD44008.1
AK176283 mRNA Translation: BAD44046.1
AK176290 mRNA Translation: BAD44053.1
AK176304 mRNA Translation: BAD44067.1
AK176329 mRNA Translation: BAD44092.1
AK221228 mRNA Translation: BAD93819.1
AK228286 mRNA Translation: BAF00232.1
FJ708761 mRNA Translation: ACN59354.1
PIRiT04492
RefSeqiNP_567870.1, NM_119274.5 [C0LGR9-1]
UniGeneiAt.31759

Genome annotation databases

EnsemblPlantsiAT4G31250.1; AT4G31250.1; AT4G31250 [C0LGR9-1]
GeneIDi829252
GrameneiAT4G31250.1; AT4G31250.1; AT4G31250 [C0LGR9-1]
KEGGiath:AT4G31250

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiY4312_ARATH
AccessioniPrimary (citable) accession number: C0LGR9
Secondary accession number(s): O49575, Q0WRL7, Q67Z85
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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