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C0LGR9 (Y4312_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase At4g31250

EC=2.7.11.1
Gene names
Ordered Locus Names:At4g31250
ORF Names:F8F16.70
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length676 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Membrane; Single-pass type I membrane protein Potential.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 5 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence CAA16528.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAB79843.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: C0LGR9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: C0LGR9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-88: Missing.
     89-98: ELDVQALGSI → MERSDVFKRL
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 Potential
Chain27 – 676650Probable LRR receptor-like serine/threonine-protein kinase At4g31250
PRO_0000387556

Regions

Topological domain27 – 242216Extracellular Potential
Transmembrane243 – 26321Helical; Potential
Topological domain264 – 676413Cytoplasmic Potential
Repeat98 – 12225LRR 1
Repeat123 – 14624LRR 2
Repeat148 – 17124LRR 3
Repeat172 – 19524LRR 4
Repeat197 – 21822LRR 5
Domain366 – 640275Protein kinase
Nucleotide binding372 – 3809ATP By similarity

Sites

Binding site3941ATP By similarity

Amino acid modifications

Modified residue3681Phosphoserine By similarity
Modified residue4461Phosphoserine By similarity
Modified residue5431Phosphoserine By similarity
Glycosylation421N-linked (GlcNAc...) Potential
Glycosylation731N-linked (GlcNAc...) Potential
Glycosylation831N-linked (GlcNAc...) Potential
Glycosylation2181N-linked (GlcNAc...) Potential

Natural variations

Alternative sequence1 – 8888Missing in isoform 2.
VSP_038293
Alternative sequence89 – 9810ELDVQALGSI → MERSDVFKRL in isoform 2.
VSP_038294

Experimental info

Sequence conflict487 – 4882DL → RI in BAF00232. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 65162EF1D0782579

FASTA67675,235
        10         20         30         40         50         60 
MTRDDKFPIV YSLLLIVLLF VSPIYGDGDA DALLKFKSSL VNASSLGGWD SGEPPCSGDK 

        70         80         90        100        110        120 
GSDSKWKGVM CSNGSVFALR LENMSLSGEL DVQALGSIRG LKSISFMRNH FEGKIPRGID 

       130        140        150        160        170        180 
GLVSLAHLYL AHNQFTGEID GDLFSGMKAL LKVHLEGNRF SGEIPESLGK LPKLTELNLE 

       190        200        210        220        230        240 
DNMFTGKIPA FKQKNLVTVN VANNQLEGRI PLTLGLMNIT FFSGNKGLCG APLLPCRYTR 

       250        260        270        280        290        300 
PPFFTVFLLA LTILAVVVLI TVFLSVCILS RRQGKGQDQI QNHGVGHFHG QVYGQPEQQQ 

       310        320        330        340        350        360 
HSEKSSQDSK VYRKLANETV QRDSTATSGA ISVGGLSPDE DKRGDQRKLH FVRNDQERFT 

       370        380        390        400        410        420 
LQDMLRASAE VLGSGGFGSS YKAALSSGRA VVVKRFRFMS NIGREEFYDH MKKIGRLSHP 

       430        440        450        460        470        480 
NLLPLIAFYY RKEEKLLVTN YISNGSLANL LHANRTPGQV VLDWPIRLKI VRGVTRGLAY 

       490        500        510        520        530        540 
LYRVFPDLNL PHGHLKSSNV LLDPNFEPLL TDYALVPVVN RDQSQQFMVA YKAPEFTQQD 

       550        560        570        580        590        600 
RTSRRSDVWS LGILILEILT GKFPANYLRQ GKGADDELAA WVESVARTEW TADVFDKEMK 

       610        620        630        640        650        660 
AGKEHEAQML KLLKIGLRCC DWDIEKRIEL HEAVDRIEEV DRDAGGGQES VRSSYVTASD 

       670 
GDHRSSRAMT EEFSLM 

« Hide

Isoform 2 [UniParc].

Checksum: A2CA3D49FE525576
Show »

FASTA58866,126

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Strain: cv. Columbia.
[4]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL021633 Genomic DNA. Translation: CAA16528.1. Sequence problems.
AL161578 Genomic DNA. Translation: CAB79843.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85882.1.
AK176198 mRNA. Translation: BAD43961.1.
AK176233 mRNA. Translation: BAD43996.1.
AK176245 mRNA. Translation: BAD44008.1.
AK176283 mRNA. Translation: BAD44046.1.
AK176290 mRNA. Translation: BAD44053.1.
AK176304 mRNA. Translation: BAD44067.1.
AK176329 mRNA. Translation: BAD44092.1.
AK221228 mRNA. Translation: BAD93819.1.
AK228286 mRNA. Translation: BAF00232.1.
FJ708761 mRNA. Translation: ACN59354.1.
PIRT04492.
RefSeqNP_567870.1. NM_119274.4. [C0LGR9-1]
UniGeneAt.31759.

3D structure databases

ProteinModelPortalC0LGR9.
SMRC0LGR9. Positions 26-256, 288-640.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEC0LGR9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G31250.1; AT4G31250.1; AT4G31250. [C0LGR9-1]
GeneID829252.
KEGGath:AT4G31250.

Organism-specific databases

GeneFarm2307. 47.
TAIRAT4G31250.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116554.
InParanoidO49575.
OMAIGMCCCE.
PhylomeDBC0LGR9.

Enzyme and pathway databases

BioCycARA:AT4G31250-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamPF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY4312_ARATH
AccessionPrimary (citable) accession number: C0LGR9
Secondary accession number(s): O49575, Q0WRL7, Q67Z85
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names