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C0LGR3 (Y4265_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable LRR receptor-like serine/threonine-protein kinase At4g26540

EC=2.7.11.1
Gene names
Ordered Locus Names:At4g26540
ORF Names:M3E9.30
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length1091 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 27 LRR (leucine-rich) repeats.

Contains 1 protein kinase domain.

Sequence caution

The sequence AAL32011.1 differs from that shown. Reason: Frameshift at position 1084.

The sequence CAA18216.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAA18216.1 differs from that shown. Reason: Frameshift at position 931.

The sequence CAB79509.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAB79509.1 differs from that shown. Reason: Frameshift at position 931.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 10911067Probable LRR receptor-like serine/threonine-protein kinase At4g26540
PRO_0000387553

Regions

Topological domain25 – 703679Extracellular Potential
Transmembrane704 – 72421Helical; Potential
Topological domain725 – 1091367Cytoplasmic Potential
Repeat33 – 5624LRR 1
Repeat67 – 9125LRR 2
Repeat92 – 11524LRR 3
Repeat116 – 14025LRR 4
Repeat142 – 16625LRR 5
Repeat168 – 18821LRR 6
Repeat190 – 21324LRR 7
Repeat214 – 23724LRR 8
Repeat239 – 26123LRR 9
Repeat262 – 28524LRR 10
Repeat287 – 30923LRR 11
Repeat311 – 33222LRR 12
Repeat333 – 35725LRR 13
Repeat359 – 38325LRR 14
Repeat385 – 40521LRR 15
Repeat406 – 42924LRR 16
Repeat431 – 45323LRR 17
Repeat454 – 47724LRR 18
Repeat478 – 50124LRR 19
Repeat503 – 52422LRR 20
Repeat525 – 54824LRR 21
Repeat549 – 57224LRR 22
Repeat574 – 59623LRR 23
Repeat598 – 62023LRR 24
Repeat621 – 64424LRR 25
Repeat645 – 66824LRR 26
Repeat669 – 69022LRR 27
Domain760 – 1046287Protein kinase
Nucleotide binding766 – 7749ATP By similarity

Sites

Active site8831Proton acceptor By similarity
Binding site7881ATP By similarity

Amino acid modifications

Modified residue8311Phosphotyrosine By similarity
Glycosylation401N-linked (GlcNAc...) Potential
Glycosylation1041N-linked (GlcNAc...) Potential
Glycosylation1631N-linked (GlcNAc...) Potential
Glycosylation3561N-linked (GlcNAc...) Potential
Glycosylation4311N-linked (GlcNAc...) Potential
Glycosylation4521N-linked (GlcNAc...) Potential
Glycosylation6041N-linked (GlcNAc...) Potential
Glycosylation6511N-linked (GlcNAc...) Potential
Glycosylation6971N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict2211L → P in AAL32011. Ref.3

Sequences

Sequence LengthMass (Da)Tools
C0LGR3 [UniParc].

Last modified May 5, 2009. Version 1.
Checksum: 061EFB0EDF281988

FASTA1,091119,529
        10         20         30         40         50         60 
MPPNIYRLSF FSSLLCFFFI PCFSLDQQGQ ALLSWKSQLN ISGDAFSSWH VADTSPCNWV 

        70         80         90        100        110        120 
GVKCNRRGEV SEIQLKGMDL QGSLPVTSLR SLKSLTSLTL SSLNLTGVIP KEIGDFTELE 

       130        140        150        160        170        180 
LLDLSDNSLS GDIPVEIFRL KKLKTLSLNT NNLEGHIPME IGNLSGLVEL MLFDNKLSGE 

       190        200        210        220        230        240 
IPRSIGELKN LQVLRAGGNK NLRGELPWEI GNCENLVMLG LAETSLSGKL PASIGNLKRV 

       250        260        270        280        290        300 
QTIAIYTSLL SGPIPDEIGY CTELQNLYLY QNSISGSIPT TIGGLKKLQS LLLWQNNLVG 

       310        320        330        340        350        360 
KIPTELGNCP ELWLIDFSEN LLTGTIPRSF GKLENLQELQ LSVNQISGTI PEELTNCTKL 

       370        380        390        400        410        420 
THLEIDNNLI TGEIPSLMSN LRSLTMFFAW QNKLTGNIPQ SLSQCRELQA IDLSYNSLSG 

       430        440        450        460        470        480 
SIPKEIFGLR NLTKLLLLSN DLSGFIPPDI GNCTNLYRLR LNGNRLAGSI PSEIGNLKNL 

       490        500        510        520        530        540 
NFVDISENRL VGSIPPAISG CESLEFLDLH TNSLSGSLLG TTLPKSLKFI DFSDNALSST 

       550        560        570        580        590        600 
LPPGIGLLTE LTKLNLAKNR LSGEIPREIS TCRSLQLLNL GENDFSGEIP DELGQIPSLA 

       610        620        630        640        650        660 
ISLNLSCNRF VGEIPSRFSD LKNLGVLDVS HNQLTGNLNV LTDLQNLVSL NISYNDFSGD 

       670        680        690        700        710        720 
LPNTPFFRRL PLSDLASNRG LYISNAISTR PDPTTRNSSV VRLTILILVV VTAVLVLMAV 

       730        740        750        760        770        780 
YTLVRARAAG KQLLGEEIDS WEVTLYQKLD FSIDDIVKNL TSANVIGTGS SGVVYRITIP 

       790        800        810        820        830        840 
SGESLAVKKM WSKEESGAFN SEIKTLGSIR HRNIVRLLGW CSNRNLKLLF YDYLPNGSLS 

       850        860        870        880        890        900 
SRLHGAGKGG CVDWEARYDV VLGVAHALAY LHHDCLPTII HGDVKAMNVL LGPHFEPYLA 

       910        920        930        940        950        960 
DFGLARTISG YPNTGIDLAK PTNRPPMAGS YGYMAPEHAS MQRITEKSDV YSYGVVLLEV 

       970        980        990       1000       1010       1020 
LTGKHPLDPD LPGGAHLVKW VRDHLAEKKD PSRLLDPRLD GRTDSIMHEM LQTLAVAFLC 

      1030       1040       1050       1060       1070       1080 
VSNKANERPL MKDVVAMLTE IRHIDVGRSE TEKIKAGGCG SKEPQQFMSN EKIINSHGSS 

      1090 
NCSFAFSDDS V 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Genome-wide cloning and sequence analysis of leucine-rich repeat receptor-like protein kinase genes in Arabidopsis thaliana."
Gou X., He K., Yang H., Yuan T., Lin H., Clouse S.D., Li J.
BMC Genomics 11:19-19(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL022223 Genomic DNA. Translation: CAA18216.1. Sequence problems.
AL161565 Genomic DNA. Translation: CAB79509.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE85216.1.
AF436829 mRNA. Translation: AAL32011.1. Frameshift.
FJ708754 mRNA. Translation: ACN59348.1.
PIRT05050.
RefSeqNP_567748.5. NM_118787.5.
UniGeneAt.20959.

3D structure databases

ProteinModelPortalC0LGR3.
SMRC0LGR3. Positions 24-1042.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEC0LGR3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G26540.1; AT4G26540.1; AT4G26540.
GeneID828760.
KEGGath:AT4G26540.

Organism-specific databases

GeneFarm624. 55.
TAIRAT4G26540.

Phylogenomic databases

eggNOGCOG4886.
HOGENOMHOG000116551.
InParanoidQ8W556.
OMADSIMHEM.
PhylomeDBC0LGR3.

Enzyme and pathway databases

BioCycARA:AT4G26540-MONOMER.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR001611. Leu-rich_rpt.
IPR013210. LRR-contain_N2.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00560. LRR_1. 2 hits.
PF13855. LRR_8. 2 hits.
PF08263. LRRNT_2. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY4265_ARATH
AccessionPrimary (citable) accession number: C0LGR3
Secondary accession number(s): O65580, Q8W556
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 5, 2009
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names